The paradox of metabolism in quiescent stem cells
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13608
Abstract: The shift between a proliferating and a nonproliferating state is associated with significant changes in metabolic needs. Proliferating cells tend to have higher metabolic rates, and their metabolic profiles facilitate biosynthesis, as compared to those… read more here.
Keywords: metabolic profiles; paradox metabolism; stem; stem cells ... See more keywords
Lysosomal Regulation of Metabolism in Quiescent Hematopoietic Stem Cells: More than Just Autophagy.
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DOI: 10.1016/j.stem.2021.02.017
Abstract: The depth of quiescence in hematopoietic stem cells (HSCs) dictates their potency and is sensitive to metabolic perturbations. Recent evidence suggests that lysosomal functions distinct from autophagic processes are pivotal in regulating quiescence versus activation… read more here.
Keywords: regulation metabolism; hematopoietic stem; lysosomal regulation; stem cells ... See more keywords