Targeting Strategies for Aberrant Lipid Metabolism Reprogramming and the Immune Microenvironment in Esophageal Cancer: A Review
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/4257359
Abstract: Esophageal cancer is of high importance to occurrence, development, and treatment resistance. As evidenced by recent studies, pathways (e.g., Wnt/β-catenin, AMPK, and Hippo) are critical to the proliferation, differentiation, and self-renewal of esophageal cancer. In… read more here.
Keywords: lipid metabolism; esophageal cancer; cancer; metabolism reprogramming ... See more keywords
The Role and Therapeutic Perspectives of Sirtuin 3 in Cancer Metabolism Reprogramming, Metastasis, and Chemoresistance
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.910963
Abstract: Sirtuin 3 (SIRT3), the nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase, acts as a metabolic modulator mainly located in mitochondria via regulating the process of the relevant biochemical processes by targeting crucial mediators. Recently, owing to its… read more here.
Keywords: reprogramming metastasis; metastasis chemoresistance; cancer; metabolism reprogramming ... See more keywords
Epigenetics and Metabolism Reprogramming Interplay into Glioblastoma: Novel Insights on Immunosuppressive Mechanisms
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DOI: 10.3390/antiox12020220
Abstract: The central nervous system represents a complex environment in which glioblastoma adapts skillfully, unleashing a series of mechanisms suitable for its efficient development and diffusion. In particular, changes in gene expression and mutational events that… read more here.
Keywords: glioblastoma novel; glioblastoma; epigenetics metabolism; interplay glioblastoma ... See more keywords
Novel strategy for oncogenic alteration-induced lipid metabolism reprogramming in pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Acta biochimica et biophysica Sinica"
DOI: 10.3724/abbs.2023045
Abstract: The pathogenesis of pancreatic cancer involves substantial metabolic reprogramming, resulting in abnormal proliferation of tumor cells. This tumorigenic reprogramming is often driven by genetic mutations, such as activating mutations of the KRAS oncogene and inactivating… read more here.
Keywords: pancreatic cancer; lipid metabolism; metabolism reprogramming; reprogramming pancreatic ... See more keywords
TBC1D8 Amplification Drives Tumorigenesis through Metabolism Reprogramming in Ovarian Cancer
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DOI: 10.7150/thno.30224
Abstract: Cancer cells undergo metabolic reprogramming to support their energy demand and biomass synthesis. However, the mechanisms driving cancer metabolism reprogramming are not well understood. Methods: The differential proteins and interacted proteins were identified by proteomics.… read more here.
Keywords: tbc1d8; aerobic glycolysis; ovarian cancer; cancer ... See more keywords