Articles with "metabolism rovatirelin" as a keyword



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Human mass balance, pharmacokinetics and metabolism of rovatirelin and identification of its metabolic enzymes in vitro

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Published in 2019 at "Xenobiotica"

DOI: 10.1080/00498254.2019.1580796

Abstract: Abstract The mass balance, pharmacokinetics and metabolism of rovatirelin were characterised in healthy male subjects after a single oral dose of [14C]rovatirelin. [14C]Rovatirelin was steadily absorbed, and the peak concentrations of radioactivity and rovatirelin were… read more here.

Keywords: balance pharmacokinetics; rovatirelin; mass balance; metabolic enzymes ... See more keywords