FOXO-mediated repression of Dicer1 regulates metabolism, stress resistance, and longevity in Drosophila.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2216539120
Abstract: The adipose tissue plays a crucial role in metabolism and physiology, affecting animal lifespan and susceptibility to disease. In this study, we present evidence that adipose Dicer1 (Dcr-1), a conserved type III endoribonuclease involved in… read more here.
Keywords: metabolism; resistance longevity; stress; metabolism stress ... See more keywords
Metformin extends the chronological lifespan of fission yeast by altering energy metabolism and stress resistance capacity
Sign Up to like & getrecommendations! Published in 2023 at "FEMS Yeast Research"
DOI: 10.1093/femsyr/foad018
Abstract: Abstract The antiaging properties of metformin used for the treatment of type-2 diabetes mellitus have been studied extensively, but there is more to discover regarding underlying mechanisms. Here, we show that metformin significantly prolongs the… read more here.
Keywords: energy metabolism; chronological lifespan; metabolism stress; lifespan ... See more keywords