Metabolism in the Tumor Microenvironment.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-44518-8_1
Abstract: From a general perspective, in the context of solid tumors, we can distinguish metabolic alterations of cancer cells from those of the stroma. These two components interact with each other and with the extracellular matrix… read more here.
Keywords: metabolic alterations; metabolism; biology; tumor microenvironment ... See more keywords
Editorial: Immuno-Metabolism in Tumor Microenvironment
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.00374
Abstract: From Hanahan and Weinberg’s original description of six hallmarks of cancer (self-sufficiency in growth signals, insensitivity to growth-inhibitory signals, evasion of apoptosis, limitless replicative potential, sustained angiogenesis, and tissue invasion and metastasis) (1), it took… read more here.
Keywords: metabolism; immuno metabolism; cancer; tumor microenvironment ... See more keywords
Lipid metabolism in tumor immunology and immunotherapy
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DOI: 10.3389/fonc.2023.1187279
Abstract: Lipids are a diverse class of biomolecules that have been implicated in cancer pathophysiology and in an array of immune responses, making them potential targets for improving immune responsiveness. Lipid and lipid oxidation also can… read more here.
Keywords: tumor immunology; metabolism tumor; lipid metabolism; cancer ... See more keywords
The role of cholesterol metabolism in tumor therapy, from bench to bed
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DOI: 10.3389/fphar.2023.928821
Abstract: Cholesterol and its metabolites have important biological functions. Cholesterol is able to maintain the physical properties of cell membrane, play an important role in cellular signaling, and cellular cholesterol levels reflect the dynamic balance between… read more here.
Keywords: tumor therapy; cholesterol; cholesterol metabolism; metabolism tumor ... See more keywords
Effects of Glucose Metabolism, Lipid Metabolism, and Glutamine Metabolism on Tumor Microenvironment and Clinical Implications
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DOI: 10.3390/biom12040580
Abstract: In recent years, an increasingly more in depth understanding of tumor metabolism in tumorigenesis, tumor growth, metastasis, and prognosis has been achieved. The broad heterogeneity in tumor tissue is the critical factor affecting the outcome… read more here.
Keywords: metabolism; metabolism tumor; effects glucose; tumor microenvironment ... See more keywords
The Epithelial–Mesenchymal Transition at the Crossroads between Metabolism and Tumor Progression
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DOI: 10.3390/ijms23020800
Abstract: The transition between epithelial and mesenchymal phenotype is emerging as a key determinant of tumor cell invasion and metastasis. It is a plastic process in which epithelial cells first acquire the ability to invade the… read more here.
Keywords: metabolism tumor; mesenchymal transition; progression; epithelial mesenchymal ... See more keywords
Lactate dehydrogenase B regulates macrophage metabolism in the tumor microenvironment
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DOI: 10.7150/thno.58380
Abstract: Background: Glucose metabolism in the tumor-microenvironment is a fundamental hallmark for tumor growth and intervention therein remains an attractive option for anti-tumor therapy. Whether tumor-derived factors such as microRNAs (miRs) regulate glucose metabolism in stromal… read more here.
Keywords: metabolism; tumor derived; mir 375; tumor microenvironment ... See more keywords