Extraordinary long detection window of a synthetic cannabinoid metabolite in human urine - potential impact on therapeutic decisions.
Sign Up to like & getrecommendations! Published in 2020 at "Drug testing and analysis"
DOI: 10.1002/dta.2770
Abstract: Synthetic cannabinoids (SCs) have become established drugs of abuse. They play an increasing role in drug therapy, where abstinence control testing is required. Differentiation between recent drug uptake and uptake in the distant past is… read more here.
Keywords: drug; metabolite; detection window; urine samples ... See more keywords
Di‐(2‐ethylhexyl) phthalate exposure induces female reproductive toxicity and alters the intestinal microbiota community structure and fecal metabolite profile in mice
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Toxicology"
DOI: 10.1002/tox.23121
Abstract: Di‐(2‐ethylhexyl) phthalate (DEHP) is one of the most commonly used plasticizers, and it is widely applied in various plastic products. DEHP is an endocrine‐disrupting chemical (EDC) that has been shown to disrupt the function of… read more here.
Keywords: exposure; toxicity; mice; female reproductive ... See more keywords
LC-MS-MS Method Development and Analysis of Stimulants, Opiates, Synthetic Opiates, PCP, and Benzodiazepines in Wastewater. Preponderance of these Drugs During Football Games.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8579-1_15
Abstract: A method was developed for the analysis of stimulant drugs, opiates, synthetic opiates, PCP, and benzodiazepines in wastewater samples using liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS). A total of 33 compounds (stimulant-type drugs… read more here.
Keywords: metabolite; primary urinary; opiates pcp; opiates synthetic ... See more keywords
Environmental monitoring and assessment of antibacterial metabolite producing actinobacteria screened from marine sediments in south coastal regions of Karnataka, India
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Monitoring and Assessment"
DOI: 10.1007/s10661-017-5999-y
Abstract: Assessment of the therapeutic potential of secondary metabolite producing microorganisms from the marine coastal areas imparts scope and application in the field of environmental monitoring. The present study aims to screen metabolites with antibacterial potential… read more here.
Keywords: environmental monitoring; south coastal; coastal regions; monitoring ... See more keywords
Nutrient-depended metabolic switching during batch cultivation of Streptomyces coelicolor explored with absolute quantitative mass spectrometry-based metabolite profiling
Sign Up to like & getrecommendations! Published in 2022 at "3 Biotech"
DOI: 10.1007/s13205-022-03146-x
Abstract: The well-known secondary metabolite-producing bacterium Streptomyces coelicolor is a natural choice for the development of super-hosts optimized for the heterologous expression of antibiotic biosynthetic gene clusters (BGCs). In this study, we used S. coelicolor M145… read more here.
Keywords: cultivation; limitation; mass; coelicolor ... See more keywords
Toward an evaluation of metabolite channeling in vivo.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2019.09.013
Abstract: Intermediates of metabolic pathways are sometimes contained within cavities of enzyme molecules and passed directly from active centers of one to next enzymes without diffusing into bulk matrix. This 'metabolite channeling' is postulated to have… read more here.
Keywords: toward evaluation; metabolite; evaluation metabolite; metabolite channeling ... See more keywords
Comprehensive hippocampal metabolite responses to PM2.5 in young mice.
Sign Up to like & getrecommendations! Published in 2018 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2018.08.080
Abstract: Fine particulate matter (PM2.5) exposure alters brain development, clinical cognition and behavior in childhood. Previous studies of this subject have mainly been epidemiological investigations or analyses of gene and protein levels; however, gas chromatography-mass spectrometry… read more here.
Keywords: pm2; metabolism; metabolite; pm2 exposure ... See more keywords
Determination of trace thiophanate-methyl and its metabolite carbendazim with teratogenic risk in red bell pepper (Capsicumannuum L.) by surface-enhanced Raman imaging technique.
Sign Up to like & getrecommendations! Published in 2017 at "Food chemistry"
DOI: 10.1016/j.foodchem.2016.09.051
Abstract: Surface-enhanced Raman scattering (SERS) imaging coupling with multivariate analysis in spectral region of 200 to 1800cm-1 was developed to quantify and visualize thiophanate-methyl (TM) and its metabolite carbendazim residues in red bell pepper (Capsicum annuum… read more here.
Keywords: surface enhanced; enhanced raman; metabolite carbendazim; thiophanate methyl ... See more keywords
Secondary metabolite profiles of small-spored Alternaria support the new phylogenetic organization of the genus.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of food microbiology"
DOI: 10.1016/j.ijfoodmicro.2018.11.022
Abstract: The group of the small-spored Alternaria species is particularly relevant in foods due to its high frequency and wide distribution in different crops. These species are responsible for the accumulation of mycotoxins and bioactive secondary… read more here.
Keywords: small spored; secondary metabolite; spored alternaria; metabolite ... See more keywords
N-Docosahexaenoylethanolamine: A neurotrophic and neuroprotective metabolite of docosahexaenoic acid.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular aspects of medicine"
DOI: 10.1016/j.mam.2018.03.004
Abstract: N-Docosahexaenoylethanolamine (synaptamide) is an endocannabinoid-like metabolite endogenously synthesized from docosahexaenoic acid (DHA, 22:6n-3), the major omega-3 polyunsaturated fatty acid present in the brain. Although its biosynthetic mechanism has yet to be established, there is a… read more here.
Keywords: docosahexaenoic acid; neuroprotective metabolite; neurotrophic neuroprotective; docosahexaenoylethanolamine neurotrophic ... See more keywords
In vitro neuroprotective potential of lichen metabolite fumarprotocetraric acid via intracellular redox modulation
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2016.12.020
Abstract: Abstract The lichen‐forming fungi Cetraria islandica has been largely used in folk medicines, and it has recently showed promising in vitro antioxidant effects in glial‐like cells. Current work aimed at investigating the neuroprotective potential of… read more here.
Keywords: lichen; fumarprotocetraric acid; metabolite; neuroprotective potential ... See more keywords