Mining the microbiota for microbial and metabolite-based immunotherapies
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Immunology"
DOI: 10.1038/s41577-019-0144-5
Abstract: Trillions of microorganisms transit through and reside in the mammalian gastrointestinal tract each day, collectively producing thousands of small molecules and metabolites with local and systemic effects on host physiology. Identifying effector microorganisms that causally… read more here.
Keywords: physiology; based immunotherapies; metabolite based; mining microbiota ... See more keywords
Metabolite‐based genome‐wide association study enables dissection of the flavonoid decoration pathway of wheat kernels
Sign Up to like & getrecommendations! Published in 2020 at "Plant Biotechnology Journal"
DOI: 10.1111/pbi.13335
Abstract: Summary The marriage of metabolomic approaches with genetic design has proven a powerful tool in dissecting diversity in the metabolome and has additionally enhanced our understanding of complex traits. That said, such studies have rarely… read more here.
Keywords: genome wide; wheat kernels; study; metabolite based ... See more keywords
Metabolic Profiling of Thymic Epithelial Tumors Hints to a Strong Warburg Effect, Glutaminolysis and Precarious Redox Homeostasis as Potential Therapeutic Targets
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14061564
Abstract: Simple Summary Thymomas and thymic carcinomas (TCs) are malignant thymic epithelial tumors (TETs) with poor outcome, if non-resectable. Metabolic signatures of TETs have not yet been studied and may offer new therapeutic options. This is… read more here.
Keywords: metabolite based; thymomas; thymic epithelial; spectroscopy ... See more keywords