Novel soil bacteria possess diverse genes for secondary metabolite biosynthesis
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DOI: 10.1038/s41586-018-0207-y
Abstract: In soil ecosystems, microorganisms produce diverse secondary metabolites such as antibiotics, antifungals and siderophores that mediate communication, competition and interactions with other organisms and the environment1,2. Most known antibiotics are derived from a few culturable… read more here.
Keywords: secondary metabolite; metabolite biosynthesis; nonribosomal peptide; soil ... See more keywords
Chromosome-Level Genome Sequences, Comparative Genomic Analyses, and Secondary-Metabolite Biosynthesis Evaluation of the Medicinal Edible Mushroom Laetiporus sulphureus
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DOI: 10.1128/spectrum.02439-22
Abstract: L. sulphureus is a parasitic basidiomycete fungus that causes brown rot. The fruiting bodies of L. sulphureus are used as ancient medicines in China and Europe to cure cancer, analgesia, cough, and rheumatism and are… read more here.
Keywords: sulphureus; biosynthesis; genome; secondary metabolite ... See more keywords
Genomic and Metabolomic Analyses of the Medicinal Fungus Inonotus hispidus for Its Metabolite’s Biosynthesis and Medicinal Application
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DOI: 10.3390/jof8121245
Abstract: Inonotus hispidus mushroom is a traditional medicinal fungus with anti-cancer, antioxidation, and immunomodulatory activities, and it is used in folk medicine as a treatment for indigestion, cancer, diabetes, and gastric illnesses. Although I. hispidus is… read more here.
Keywords: biosynthesis; inonotus hispidus; hispidus; medicinal fungus ... See more keywords
Integrative Analysis of the Transcriptome and Metabolome Reveals the Developmental Mechanisms and Metabolite Biosynthesis of the Tuberous Roots of Tetrastigma hemsleyanum
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DOI: 10.3390/molecules28062603
Abstract: The tuberous root of Tetrastigma hemsleyanum Diels et Gilg (T. hemsleyanum) is a traditional Chinese medicine with a wide range of clinical applications. However, the scarcity of its wild resources, its low yield, and the… read more here.
Keywords: tetrastigma hemsleyanum; hemsleyanum; biosynthesis; mechanisms metabolite ... See more keywords