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Published in 2019 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2019.09.013
Abstract: Intermediates of metabolic pathways are sometimes contained within cavities of enzyme molecules and passed directly from active centers of one to next enzymes without diffusing into bulk matrix. This 'metabolite channeling' is postulated to have…
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Keywords:
toward evaluation;
metabolite;
evaluation metabolite;
metabolite channeling ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0172673
Abstract: Metabolite or substrate channeling is a direct transfer of metabolites from one enzyme to the next enzyme in a cascade. Among many potential advantages of substrate channeling, acceleration of the total reaction rate is considered…
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Keywords:
channeling accelerate;
cascade reactions;
enzyme catalyzed;
catalyzed cascade ... See more keywords