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Single‐ and Multiple‐Day Dosing Studies to Investigate High‐Dose Pharmacokinetics of Epelsiban and Its Metabolite, GSK2395448, in Healthy Female Volunteers

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Published in 2018 at "Clinical Pharmacology in Drug Development"

DOI: 10.1002/cpdd.363

Abstract: Open‐label single‐ and double‐blind repeat‐dose studies in healthy female volunteers were conducted to investigate the pharmacokinetics (PK) and safety/tolerability of epelsiban total daily doses ranging from 600 to 900 mg. In 1 study (n =… read more here.

Keywords: healthy female; gsk2395448; epelsiban metabolite; metabolite gsk2395448 ... See more keywords