New K50R mutant mouse models reveal impaired hypusination of eif5a2 with alterations in cell metabolite landscape
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DOI: 10.1242/bio.059647
Abstract: ABSTRACT The eukaryotic translation initiation factor 5A1 (eIF5A1) and 5A2 (eIF5A2) are important proteins in a variety of physiological and pathophysiological processes and their function has been linked to neurodevelopmental disorders, cancer, and viral infections.… read more here.
Keywords: mouse; metabolite landscape; eif5a2; k50r mutant ... See more keywords