Metabolite profiling of whole murine embryos reveals metabolic perturbations associated with maternal valproate-induced neural tube closure defects.
Sign Up to like & getrecommendations! Published in 2017 at "Birth defects research"
DOI: 10.1002/bdra.23583
Abstract: BACKGROUND Valproic acid (VPA) is prescribed therapeutically for multiple conditions, including epilepsy. When taken during pregnancy, VPA is teratogenic, increasing the risk of several birth and developmental defects including neural tube defects (NTDs). The mechanism… read more here.
Keywords: vpa; embryos; neural tube; tube closure ... See more keywords
Metabolite profiling and isolation of biologically active compounds from Scadoxus puniceus, a highly traded South African medicinal plant
Sign Up to like & getrecommendations! Published in 2018 at "Phytotherapy Research"
DOI: 10.1002/ptr.6000
Abstract: Scadoxus puniceus (Amaryllidaceae), a medicinal plant of high value in South Africa, is used as a component of a traditional herbal tonic prescribed to treat several ailments. Ultra‐high performance liquid chromatography–tandem mass spectrometry quantified the… read more here.
Keywords: scadoxus puniceus; puniceus; active compounds; metabolite profiling ... See more keywords
Metabolite profiling study on the toxicological effects of polybrominated diphenyl ether in a rat model
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Toxicology"
DOI: 10.1002/tox.22322
Abstract: Polybrominated diphenyl ethers (PBDEs) are commonly used to retard the combustion of materials such as foam padding, textiles, or plastics, and numerous studies have confirmed the accumulation thereof in the environment and in fish, mammals,… read more here.
Keywords: polybrominated diphenyl; pbde 209; metabolite profiling; profiling study ... See more keywords
Metabolite profiling of wines made from disease-tolerant varieties
Sign Up to like & getrecommendations! Published in 2019 at "European Food Research and Technology"
DOI: 10.1007/s00217-019-03314-z
Abstract: Disease-tolerant varieties of Vitis vinifera are receiving great attention due to their great potential in significantly reducing the application of chemical products as well as the production costs in viticulture. The aim of this study… read more here.
Keywords: disease tolerant; tolerant varieties; wines made; disease ... See more keywords
Metabolite profiling of violet, white and pink flowers revealing flavonoids composition patterns in Rhododendron pulchrum Sweet
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biosciences"
DOI: 10.1007/s12038-020-00125-3
Abstract: Flower color is the major characteristics and critical breeding program for most Rhododendron species. However, little is known about their coloration mechanism and color inheritance. In this study, petal pigment constituents of three Rhododendron pulchrum… read more here.
Keywords: profiling violet; rhododendron pulchrum; metabolite profiling; composition ... See more keywords
Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI DIRECT study
Sign Up to like & getrecommendations! Published in 2020 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2020.102932
Abstract: Summary Background Dietary advice remains the cornerstone of prevention and management of type 2 diabetes (T2D). However, understanding the efficacy of dietary interventions is confounded by the challenges inherent in assessing free living diet. Here… read more here.
Keywords: dietary metabolite; tpred score; metabolic risk; metabolite profiling ... See more keywords
Metabolite profiling for model cultivars of wheat and rice under ozone pollution
Sign Up to like & getrecommendations! Published in 2020 at "Environmental and Experimental Botany"
DOI: 10.1016/j.envexpbot.2020.104214
Abstract: Abstract As essential source for human consumption, plants of wheat and rice are highly sensitive to ozone (O3), resulting in significant agricultural losses under O3 pollution. According to our results, photosynthesis and shoot biomass of… read more here.
Keywords: model cultivars; rice; pollution; metabolite profiling ... See more keywords
Urine metabolite profiling of Indian Antarctic Expedition members: NMR spectroscopy-based metabolomic investigation
Sign Up to like & getrecommendations! Published in 2021 at "Heliyon"
DOI: 10.1016/j.heliyon.2021.e07114
Abstract: The southernmost region of earth, Antarctica, has world's most challenging environments. Those who live for long time and work in Antarctic stations are subjected to environmental stresses such as cold weather, photoperiod variations leading to… read more here.
Keywords: expedition; urine metabolite; profiling indian; nmr spectroscopy ... See more keywords
Comparative metabolite profiling of Callistemon macropunctatus and Callistemon subulatus volatiles from different geographical origins
Sign Up to like & getrecommendations! Published in 2020 at "Industrial Crops and Products"
DOI: 10.1016/j.indcrop.2020.112222
Abstract: Abstract Since ancient times, essential oils from medicinal plants have supplied a huge repository of secondary metabolites. Genus Callistemon, Myrtaceae, was described to have nematicidal, antithrombotic, antistaphylococcal, antioxidant, and insecticidal activities. In this study we… read more here.
Keywords: callistemon subulatus; comparative metabolite; callistemon; metabolite profiling ... See more keywords
Structural characterization and discrimination of Ophiopogon japonicas (Liliaceae) from different geographical origins based on metabolite profiling analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113212
Abstract: The root tuber of Ophiopogon japonicus (Thunb.) Ker-Gawl ("Maidong" in Chinese), with steroidal saponins and homoisoflavonoids as its representative chemical compositions, is a representative medicinal herbs with multiple major producing areas. This study aimed to… read more here.
Keywords: steroidal saponins; analysis; metabolite profiling; geographical origins ... See more keywords
Accelerating Metabolite Identification in Natural Product Research: Toward an Ideal Combination of Liquid Chromatography-High-Resolution Tandem Mass Spectrometry and NMR Profiling, in Silico Databases, and Chemometrics.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b05112
Abstract: The rapid innovations in metabolite profiling, bioassays and chemometrics have led to a paradigm shift in natural product (NP) research. Indeed, having partial or full structure information about possibly "all" specialized metabolites and an estimation… read more here.
Keywords: research; natural product; metabolite profiling; identification ... See more keywords