Synthesis of a Human Urinary Metabolite of Prostaglandin D2.
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DOI: 10.1021/acs.orglett.9b03983
Abstract: A chemical synthesis of the major human metabolite of prostaglandin D2, tricyclic-PGDM, is described. The synthetic route starts from iodocyclopentenone 1 (available from cyclopentadiene in 6 steps) and requires 13 synthetic transformations. The synthetic route… read more here.
Keywords: metabolite prostaglandin; synthesis human; human urinary; metabolite ... See more keywords