1H–MRS processing parameters affect metabolite quantification: The urgent need for uniform and transparent standardization
Sign Up to like & getrecommendations! Published in 2017 at "NMR in Biomedicine"
DOI: 10.1002/nbm.3804
Abstract: Proton magnetic resonance spectroscopy (1H–MRS) can be used to quantify in vivo metabolite levels, such as lactate, γ‐aminobutyric acid (GABA) and glutamate (Glu). However, there are considerable analysis choices which can alter the accuracy or… read more here.
Keywords: metabolite quantification; processing; mrs; pcr ... See more keywords
Metabolite quantification by NMR and LC‐MS/MS reveals differences between unstimulated, stimulated, and pure parotid saliva
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2017.03.037
Abstract: &NA; Saliva is a readily available biofluid that is sensitive to metabolic changes and can be collected through rapid and non‐invasive collection procedures, and it shows great promise for clinical metabolomic studies. This work studied… read more here.
Keywords: metabolite quantification; analysis; parotid; parotid saliva ... See more keywords
Robust Metabolite Quantification from J-Compensated 2D 1H-13C-HSQC Experiments
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DOI: 10.3390/metabo10110449
Abstract: The spectral resolution of 2D 1H-13C heteronuclear single quantum coherence (1H-13C-HSQC) nuclear magnetic resonance (NMR) spectra facilitates both metabolite identification and quantification in nuclear magnetic resonance-based metabolomics. However, quantification is complicated by variations in magnetization… read more here.
Keywords: metabolite quantification; robust metabolite; hsqc; 13c hsqc ... See more keywords