High-fat diet-induced acceleration of osteoarthritis is associated with a distinct and sustained plasma metabolite signature
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-07963-6
Abstract: Metabolic changes induced by high fat diet (HFD) that contribute to osteoarthritis (OA) are poorly understood. We investigated longitudinal changes to metabolites and their contribution to OA pathogenesis in response to HFD. HFD-fed mice exhibited… read more here.
Keywords: fat diet; metabolite signature; distinct sustained; fed mice ... See more keywords
A salivary metabolite signature that reflects gingival host-microbe interactions: instability predicts gingivitis susceptibility
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DOI: 10.1038/s41598-020-59988-z
Abstract: Several proteins and peptides in saliva were shown to stimulate gingival wound repair, but the role of salivary metabolites in this process remains unexplored. In vitro gingival re-epithelialization kinetics were determined using unstimulated saliva samples… read more here.
Keywords: metabolite signature; microbe interactions; host microbe; signature ... See more keywords
Metabolite Signature of Physical Activity and the Risk of Type 2 Diabetes in 7271 Men
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DOI: 10.3390/metabo12010069
Abstract: Large population-based studies investigating the association of physical activity (PA) with the metabolite signature contribute significantly to the understanding of the effects of PA on metabolic pathways associated with the risk of type 2 diabetes.… read more here.
Keywords: metabolite signature; risk type; type diabetes; physical activity ... See more keywords
Plasma Metabolite Signature Classifies Male LRRK2 Parkinson’s Disease Patients
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DOI: 10.3390/metabo12020149
Abstract: Parkinson’s disease (PD) is a progressive neurodegenerative disease, causing loss of motor and nonmotor function. Diagnosis is based on clinical symptoms that do not develop until late in the disease progression, at which point the… read more here.
Keywords: male lrrk2; metabolite signature; disease; plasma metabolite ... See more keywords