The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Cell metabolism"
DOI: 10.1016/j.cmet.2022.02.010
Abstract: Immunotherapy has achieved limited success in patients with triple-negative breast cancer (TNBC), an aggressive disease with a poor prognosis. Commensal microbiota have been proven to colonize the mammary gland, but whether and how they modulate… read more here.
Keywords: triple negative; metabolite trimethylamine; negative breast; breast cancer ... See more keywords
MO185THE GUT MICROBIOME-DERIVED METABOLITE TRIMETHYLAMINE N-OXIDE AS A POTENTIAL BIOMARKER IN LUPUS NEPHRITIS PATIENTS
Sign Up to like & getrecommendations! Published in 2021 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfab092.0063
Abstract: Both human and animal studies suggest that the gut microbe-derived metabolite Trimethylamine N-oxide (TMAO) is strongly associated with several autoimmune disease including Rheumatoid arthritis and psoriatic arthropathy. TMAO has been previously studied as a discriminator… read more here.
Keywords: trimethylamine; lupus nephritis; metabolite trimethylamine; derived metabolite ... See more keywords
Circulating Gut Microbiota Metabolite Trimethylamine N-Oxide (TMAO) and Changes in Bone Density in Response to Weight Loss Diets: The POUNDS Lost Trial
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes Care"
DOI: 10.2337/dc19-0134
Abstract: OBJECTIVE Type 2 diabetes is related to obesity and altered bone health, and both are affected by gut microbiota. We examined associations of weight loss diet–induced changes in a gut microbiota–related metabolite trimethylamine N-oxide (TMAO),… read more here.
Keywords: weight loss; tmao; gut microbiota; metabolite trimethylamine ... See more keywords