Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the Future
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DOI: 10.1124/dmd.122.000860
Abstract: Xenobiotic receptors, such as the pregnane X receptor, regulate multiple host physiologic pathways including xenobiotic metabolism, certain aspects of cellular metabolism, and innate immunity. These ligand-dependent nuclear factors regulate gene expression via genomic recognition of… read more here.
Keywords: drugs future; metabolism; metabolites ligands; microbial metabolites ... See more keywords