Immunosuppressive metabolites in tumoral immune evasion: redundancies, clinical efforts, and pathways forward
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DOI: 10.1136/jitc-2021-003013
Abstract: Tumors accumulate metabolites that deactivate infiltrating immune cells and polarize them toward anti-inflammatory phenotypes. We provide a comprehensive review of the complex networks orchestrated by several of the most potent immunosuppressive metabolites, highlighting the impact… read more here.
Keywords: metabolites tumoral; tumoral immune; immune evasion; evasion redundancies ... See more keywords