Integrated transcriptomic and metabolomic analysis reveals adaptive changes of hibernating retinas
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26030
Abstract: Hibernation is a seasonally adaptive strategy that allows hibernators to live through extremely cold conditions. Despite the profound reduction of blood flow to the retinas, hibernation causes no lasting retinal injury. Instead, hibernators show an… read more here.
Keywords: transcriptomic metabolomic; analysis; hibernating retinas; hibernation ... See more keywords
Metabolomic analysis reveals the influences of IC50 vitamin D3 on RAW264.7 cells based on 1 H NMR and UPLC-MS/MS.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.11882
Abstract: BACKGROUND As a lipid-soluble vitamin necessary for normal human physiology, vitamin D is mostly used in fortified foods, medicines, and adjuvant treatment of diseases. However, taken in high doses, vitamin D can be toxic. METHODS… read more here.
Keywords: nmr uplc; analysis reveals; ic50 vitamin; metabolomic analysis ... See more keywords
Metabolomic analysis of pollen from honey bee hives and from canola flowers
Sign Up to like & getrecommendations! Published in 2018 at "Metabolomics"
DOI: 10.1007/s11306-018-1381-5
Abstract: Background and aimsPollen is essential for successful plant reproduction and critical for plant-pollinator mutualisms, as pollen is essential larval nutrition. However, we understand very little about the chemical constituents of pollen leading us to this exploratory study… read more here.
Keywords: pollen; plant; beehive pollen; pollen honey ... See more keywords
Metabolomic analysis of urine samples by UHPLC-QTOF-MS: Impact of normalization strategies.
Sign Up to like & getrecommendations! Published in 2017 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2016.12.029
Abstract: Among the various biological matrices used in metabolomics, urine is a biofluid of major interest because of its non-invasive collection and its availability in large quantities. However, significant sources of variability in urine metabolomics based… read more here.
Keywords: impact; analysis urine; urine samples; normalization ... See more keywords
Metabolomic analysis reveals metabolic alterations of human peripheral blood lymphocytes by perfluorooctanoic acid.
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2019.124810
Abstract: Perfluorooctanoic acid (PFOA) is a dispersive persistent organic pollutant in the environment. Accumulating reports suggest that PFOA is toxic to human lymphocytes; however, the toxicological effects of PFOA on these cells remain largely unclear. In… read more here.
Keywords: perfluorooctanoic acid; human peripheral; analysis; blood lymphocytes ... See more keywords
Metabolite tracking to elucidate the effects of environmental pollutants.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2019.05.024
Abstract: The purpose of this study was to determine whether behavioral tests and metabolic profiling of organisms can be promising alternatives for assessing the health of aquatic systems. Water samples from four potential pollution sources in… read more here.
Keywords: water; analysis; water samples; metabolomic analysis ... See more keywords
P2.02-009 Metabolomic Analysis in Lung Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Thoracic Oncology"
DOI: 10.1016/j.jtho.2017.09.1186
Abstract: a median OS of not reached so far and 14.6 months respectively (P1⁄40.20). Conclusion: STK11 mutations represent a distinct subset of NSCLC. NGS showed that STK11 mutations commonly co-existed with other driver genes. Our results… read more here.
Keywords: stk11 mutations; 009 metabolomic; lung cancer; metabolomic analysis ... See more keywords
Chlorophyll fluorescence, dark respiration and metabolomic analysis of Halodule pinifolia reveal potential heat responsive metabolites and biochemical pathways under ocean warming.
Sign Up to like & getrecommendations! Published in 2020 at "Marine environmental research"
DOI: 10.1016/j.marenvres.2020.105248
Abstract: Seagrasses are submerged marine angiosperms often prone to various biotic and abiotic stress factors in the marine environment. Our study investigated the response, adaptation and underlying tolerance mechanism of tropical seagrass Halodule pinifolia upon temperature… read more here.
Keywords: heat; dark respiration; stress; metabolomic analysis ... See more keywords
Integrated transcriptomic and metabolomic analysis of Rhizopus oryzae with different morphologies
Sign Up to like & getrecommendations! Published in 2018 at "Process Biochemistry"
DOI: 10.1016/j.procbio.2017.10.001
Abstract: In trying to discover the potential genes or strategies used to regulate the morphology of Rhizopus oryzae, cells in different morphological states were subjected to transcriptomic and metabolomic analyses. The results showed that the tricarboxylic… read more here.
Keywords: transcriptomic metabolomic; integrated transcriptomic; analysis rhizopus; rhizopus oryzae ... See more keywords
Metabolomic Analysis of Liver Tissues for Characterization of Hepatocellular Carcinoma.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.9b00185
Abstract: Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer causing more than half a million annual deaths world-wide. Understanding the molecular mechanisms contributing to HCC development and progression is highly desirable for… read more here.
Keywords: hepatocellular carcinoma; metabolomic analysis; hcc; liver ... See more keywords
Cross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor
Sign Up to like & getrecommendations! Published in 2022 at "Cell Discovery"
DOI: 10.1038/s41421-021-00361-3
Abstract: Regenerative capacity declines throughout evolution and with age. In this study, we asked whether metabolic programs underlying regenerative capability might be conserved across species, and if so, whether such metabolic drivers might be harnessed to… read more here.
Keywords: regenerative capacity; cross species; metabolomic analysis; stem cells ... See more keywords