Training grapevines generates a metabolomic signature of wine.
Sign Up to like & getrecommendations! Published in 2021 at "Food chemistry"
DOI: 10.1016/j.foodchem.2021.130665
Abstract: Training systems are an option to handle the pronounced apical dominance of grapevines and to influence diverse traits of the corresponding wine. However, it is still unclear if different training systems generate signatures in the… read more here.
Keywords: metabolomic signature; training systems; different training; wine ... See more keywords
The Metabolomic Signature of Opa1 Deficiency in Rat Primary Cortical Neurons Shows Aspartate/Glutamate Depletion and Phospholipids Remodeling
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-42554-7
Abstract: Pathogenic variants of OPA1, which encodes a dynamin GTPase involved in mitochondrial fusion, are responsible for a spectrum of neurological disorders sharing optic nerve atrophy and visual impairment. To gain insight on OPA1 neuronal specificity,… read more here.
Keywords: metabolomic signature; glutamate; aspartate glutamate; deficiency ... See more keywords
Metabolomic signature of genetic potential for muscularity in beef cattle.
Sign Up to like & getrecommendations! Published in 2021 at "Animal biotechnology"
DOI: 10.1080/10495398.2021.1894164
Abstract: The aim of this study was to investigate the serum and meat metabolomic changes according to the genetic potential for muscularity of non-castrated Nellore males and its association with phenotypic traits. Forty-eight non-castrated Nellore males… read more here.
Keywords: metabolomic signature; muscularity; signature genetic; meat ... See more keywords
A plasma metabolomic signature of Leber hereditary optic neuropathy showing taurine and nicotinamide deficiencies
Sign Up to like & getrecommendations! Published in 2021 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddab013
Abstract: Abstract Leber’s hereditary optic neuropathy (LHON) is the most common disorder due to mitochondrial DNA mutations and complex I deficiency. It is characterized by an acute vision loss, generally in young adults, with a higher… read more here.
Keywords: metabolomic signature; nicotinamide deficiencies; taurine nicotinamide; hereditary optic ... See more keywords
Metabolomic signature of the Dravet syndrome: A genetic mouse model study
Sign Up to like & getrecommendations! Published in 2021 at "Epilepsia"
DOI: 10.1111/epi.16976
Abstract: Alterations in metabolic homeostasis can contribute to neuronal hyperexcitability and seizure susceptibility. Although the pivotal role of impaired bioenergetics is obvious in metabolic epilepsies, there is a gap of knowledge regarding secondary changes in metabolite… read more here.
Keywords: metabolomic signature; genetic mouse; syndrome genetic; signature dravet ... See more keywords
Finding the metabolomic signature of drought resistance in poplar.
Sign Up to like & getrecommendations! Published in 2020 at "Physiologia plantarum"
DOI: 10.1111/ppl.13071
Abstract: Efforts to decipher the processes underpinning biological systems now have a plethora of approaches from which to choose. Transcriptomics and proteomics provide a global snapshot of the abundance of gene products in a sample, from… read more here.
Keywords: metabolomic signature; drought; drought resistance; resistance poplar ... See more keywords
A metabolomic signature for predicting chemosensitivity in gastric cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e15504
Abstract: e15504Background: Perioperative chemotherapy (QT) with platinum and fluoropyrimidines with or without anthracyclines is recommended option in patients with resectable gastric cancer (GC) at least c... read more here.
Keywords: predicting chemosensitivity; metabolomic signature; chemosensitivity gastric; gastric cancer ... See more keywords
Cecal Metabolomic Fingerprint of Unscathed Rats: Does It Reflect the Good Response to a Provocative Decompression?
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.882944
Abstract: On one side, decompression sickness (DCS) with neurological disorders lead to a reshuffle of the cecal metabolome of rats. On the other side, there is also a specific and different metabolomic signature in the cecum… read more here.
Keywords: hyperbaric protocol; cecal metabolome; decompression; metabolomic signature ... See more keywords
A Metabolomic Signature of Obesity and Risk of Colorectal Cancer: Two Nested Case–Control Studies
Sign Up to like & getrecommendations! Published in 2023 at "Metabolites"
DOI: 10.3390/metabo13020234
Abstract: Obesity is a leading contributor to colorectal cancer (CRC) risk, but the metabolic mechanisms linking obesity to CRC are not fully understood. We leveraged untargeted metabolomics data from two 1:1 matched, nested case–control studies for… read more here.
Keywords: signature; signature obesity; risk; metabolomic signature ... See more keywords
Metabolomic Signature Discriminates Normal Human Cornea from Keratoconus—A Pilot GC/MS Study
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25122933
Abstract: The molecular etiology of keratoconus (KC), a pathological condition of the human cornea, remains unclear. The aim of this work was to perform profiling of metabolites and identification of features discriminating this pathology from the… read more here.
Keywords: human cornea; metabolomic signature; cornea; pathology ... See more keywords