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Published in 2018 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2017.11.018
Abstract: A myelin basic protein (MBP)-induced experimental allergic encephalomyelitis (EAE) involves paraplegia due to a reversible thoracolumbar spinal cord impairment. The aims of this study were thus to find significant metabolic biomarkers of inflammation and identify…
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Keywords:
allergic encephalomyelitis;
experimental allergic;
metabolomics approaches;
approaches experimental ... See more keywords
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Published in 2022 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.1c01110
Abstract: Stony corals (Scleractinia) are invertebrates that form symbiotic relationships with eukaryotic algal endosymbionts and the prokaryotic microbiome. The microbiome has the potential to produce bioactive natural products providing defense and resilience to the coral host…
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Keywords:
dereplicate natural;
coral derived;
natural products;
metabolomics approaches ... See more keywords
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Published in 2019 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.9b00808
Abstract: Integrating MS-based metabolomics approaches, LC-MS-PCA and molecular networking enabled the targeted isolation of five new pyrrole-derived alkaloids, phallusialides A-E (1-5), from a marine-derived Micromonospora sp. bacterium. The structures of 1-5 were elucidated by analysis of…
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Keywords:
derived alkaloids;
metabolomics approaches;
pyrrole derived;
based metabolomics ... See more keywords
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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.805782
Abstract: Fluxomics is an innovative -omics research field that measures the rates of all intracellular fluxes in the central metabolism of biological systems. Fluxomics gathers data from multiple different -omics fields, portraying the whole picture of…
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Keywords:
monitor metabolic;
new metabolomics;
pharmacology;
metabolomics approaches ... See more keywords
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Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24033025
Abstract: To explore changes in proteins and metabolites under stress circumstances, genomics, proteomics, and metabolomics methods are used. In-depth research over the previous ten years has gradually revealed the fundamental processes of plants’ responses to environmental…
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Keywords:
stress;
proteomics metabolomics;
metabolomics approaches;
abiotic stress ... See more keywords
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Published in 2022 at "Molecules"
DOI: 10.3390/molecules27227937
Abstract: The liquid chromatography–mass spectrometry (LC-MS)-based metabolomics approach is a powerful technology for discovering novel biologically active molecules. In this study, we investigated the metabolic profiling of Orchidaceae species using LC-HRMS/MS data combined with chemometric methods…
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Keywords:
antifungal compounds;
orchidaceae;
metabolomics approaches;
based metabolomics ... See more keywords