Metabolomics‐based classification reveals subtypes of hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23455
Abstract: Hepatocellular carcinoma (HCC) is the second leading cause of cancer‐related death, and the prognosis varies due to its high heterogeneity, systematic evaluation of HCC is mainly based on genomic and transcriptomic features, metabolomics‐based classification has… read more here.
Keywords: metabolomics based; hepatocellular carcinoma; based classification; prognosis ... See more keywords
A Metabolomics-Based Approach to Identify Lineage Guiding Molecules in Pericyte Cultures.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1056-5_5
Abstract: We report the use of self-assembled peptide (F2/S) hydrogels and cellular metabolomics to identify a number of innate molecules that are integral to the metabolic processes which drive cellular differentiation of multipotent pericyte stem cells. The… read more here.
Keywords: approach identify; differentiation; approach; based approach ... See more keywords
High-Throughput Metabolomics Based on Direct Mass Spectrometry Analysis in Biomedical Research.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9236-2_3
Abstract: Metabolomics based on direct mass spectrometry analysis shows a great potential in biomedical research because of its high-throughput screening capability and wide metabolome coverage. This chapter contains detailed protocols to perform comprehensive metabolomic fingerprinting of… read more here.
Keywords: spectrometry analysis; direct mass; mass spectrometry; based direct ... See more keywords
A strategy for the metabolomics-based screening of active constituents and quality consistency control for natural medicinal substance toad venom.
Sign Up to like & getrecommendations! Published in 2018 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2018.05.054
Abstract: Natural medicinal substances (NMS) have great inconsistency due to chemical variability, seriously limiting their development as therapeutics. Here, we chose toad venom with anti-tumor activities as a model and developed a pipeline of metabolomics-based screening… read more here.
Keywords: toad venom; venom; control; natural medicinal ... See more keywords
Untargeted metabolomics based on ultra-high-performance liquid chromatography-high-resolution mass spectrometry merged with chemometrics: A new predictable tool for an early detection of mycotoxins.
Sign Up to like & getrecommendations! Published in 2017 at "Food chemistry"
DOI: 10.1016/j.foodchem.2016.11.132
Abstract: In order to explore the early detection of mycotoxins in wheat three standardized approaches (Fusarium disease severity, PCR assays for Fusarium spp. identification and mycotoxin quantification) and a novel untargeted metabolomics strategy were jointly assessed.… read more here.
Keywords: early detection; based ultra; detection mycotoxins; metabolomics based ... See more keywords
Metabolomics based on UHPLC-Orbitrap-MS and GNPS molecular networking reveals effects of time scale and environment of storage on the metabolites and taste quality of raw Pu-erh tea.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b05314
Abstract: Raw Pu-erh tea (RPT) needs ageing before drinking. However, the influence from environment and time of storage on chemical profile and flavor of RPT is unclear. In this study, the RPTs stored in wet-hot or… read more here.
Keywords: based uhplc; uhplc orbitrap; raw erh; erh tea ... See more keywords
Developing preliminary blood metabolomics-based biomarkers of insufficient sleep in humans.
Sign Up to like & getrecommendations! Published in 2020 at "Sleep"
DOI: 10.1093/sleep/zsz321
Abstract: STUDY OBJECTIVE Identify small molecule biomarkers of insufficient sleep using untargeted plasma metabolomics in humans undergoing experimental insufficient sleep. METHODS We conducted a cross-over laboratory study where 16 normal weight participants (8 men; age 22… read more here.
Keywords: biomarkers insufficient; insufficient sleep; based biomarkers; sleep ... See more keywords
Aromatic amino acids play a harmonizing role in prostate cancer: A metabolomics-based cross-sectional study
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Reproductive Biomedicine"
DOI: 10.18502/ijrm.v19i8.9622
Abstract: Abstract Background Prostate cancer (PCa) is a common health problem worldwide. The rate of this disease is likely to grow by 2021. PCa is a heterogeneous disorder, and various biochemical factors contribute to the development… read more here.
Keywords: cross sectional; metabolism; prostate cancer; study ... See more keywords
Metabolomics-based investigation of SARS-CoV-2 vaccination (Sinovac) reveals an immune-dependent metabolite biomarker
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.954801
Abstract: SARS-CoV-2 and its mutant strains continue to rapidly spread with high infection and fatality. Large-scale SARS-CoV-2 vaccination provides an important guarantee for effective resistance to existing or mutated SARS-CoV-2 virus infection. However, whether the host… read more here.
Keywords: vaccination; based investigation; metabolomics based; sars cov ... See more keywords
Metabolomics-Based Frailty Biomarkers in Older Chinese Adults
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.830723
Abstract: Background/Objectives Owing to accelerated population aging, health in older adults is becoming increasingly important. Frailty can reflect the health status and disease risks of older adults; however, appropriate biomarkers for early screening of frailty have… read more here.
Keywords: older adults; frailty biomarkers; metabolomics based; biomarkers older ... See more keywords
An Ancient Residue Metabolomics-Based Method to Distinguish Use of Closely Related Plant Species in Ancient Pipes
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2020.00133
Abstract: Residues from ancient artifacts can help identify which plant species were used for their psychoactive properties, providing important information regarding the deep-time co-evolutionary relationship between plants and humans. However, relying on the presence or absence… read more here.
Keywords: closely related; plant; ancient residue; plant species ... See more keywords