Metabolomics combined with pattern recognition and bioinformatics analysis methods for the development of pharmacodynamic biomarkers on liver fibrosis.
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DOI: 10.1039/c7mb00093f
Abstract: The major obstacle for the development of targeted therapies is the lack of pharmacodynamic (PD) biomarkers to provide an early readout of biological activities. As the modulation of metabolites may reflect the biological changes occurring… read more here.
Keywords: pharmacodynamic biomarkers; fibrosis; liver fibrosis; combined pattern ... See more keywords
Metabolomics Combined with Proteomics Provide a Novel Interpretation of the Changes in Flavonoid Glycosides during White Tea Processing
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DOI: 10.3390/foods11091226
Abstract: In this study, nonvolatile metabolomics and proteomics were applied to investigate the change mechanism of flavonoid glycoside compounds during withering processing of white tea. With the extension of withering time, the content of the main… read more here.
Keywords: provide novel; flavonoid glycosides; withering process; tea ... See more keywords