GC–MS-based metabolomics identifies an amino acid signature of acute ischemic stroke
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.01.039
Abstract: Ischemic stroke is a serious public health problem worldwide. Here, we characterized the metabolite features of acute ischemic stroke (AIS) using a gas chromatography-mass spectrometry-based metabolomics. Forty AIS patients and 29 sex and age-matched controls… read more here.
Keywords: ischemic stroke; amino acid; acute ischemic; based metabolomics ... See more keywords
TARGETED METABOLOMICS IDENTIFIES ELEVATED SEROTONIN LEVELS IN CARRIERS OF A TCF7L2 DIABETES-RISK ALLELE
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(19)32725-1
Abstract: The transcription factor 7-like 2 (TCF7L2) is part of the Wnt signaling pathway. Its polymorphism rs7903146 is associated with risk for metabolic diseases, primarily diabetes, whereas the molecular mechanisms explaining how TCF7L2 impacts metabolism have… read more here.
Keywords: elevated serotonin; levels carriers; metabolomics identifies; serotonin levels ... See more keywords
Plasma Metabolomics Identifies the Dysregulated Metabolic Profile of Primary Immune Thrombocytopenia (ITP) Based on GC-MS
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.845275
Abstract: ITP is a common autoimmune bleeding disorder with elusive pathogenesis. Our study was implemented to profile the plasma metabolic alterations of patients diagnosed with ITP, aiming at exploring the potential novel biomarkers and partial mechanism… read more here.
Keywords: plasma metabolomics; itp patients; itp; metabolomics identifies ... See more keywords