Complementary hepatic metabolomics and proteomics reveal the adaptive mechanisms of dairy cows to the transition period.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of dairy science"
DOI: 10.3168/jds.2022-22224
Abstract: The transition period from late pregnancy to early lactation is a vital time of the lifecycle of dairy cows due to the marked metabolic challenges. Besides, the liver is the pivot point of metabolism in… read more here.
Keywords: metabolomics proteomics; transition; dairy cows; transition period ... See more keywords
Integrated Metabolomics and Proteomics Analysis Reveals Plasma Lipid Metabolic Disturbance in Patients With Parkinson’s Disease
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2020.00080
Abstract: Parkinson’s disease (PD) is a common neurodegenerative disease in the elderly with a pathogenesis that remains unclear. We aimed to explore its pathogenesis through plasma integrated metabolomics and proteomics analysis. The clinical data of consecutively… read more here.
Keywords: ontology; metabolomics proteomics; analysis; disease ... See more keywords
Integrative Metabolomics, Proteomics and Transcriptomics Analysis Reveals Liver Toxicity of Mesoporous Silica Nanoparticles
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.835359
Abstract: As pharmaceutical excipients, mesoporous silica nanoparticles (MSNs) have attracted considerable concern based on potential risks to the public. The impact of MSNs on biochemical metabolism is poorly understood, and few studies have compared the effects… read more here.
Keywords: mesoporous silica; intravenous injection; msns; metabolomics proteomics ... See more keywords
Convergence of Plasma Metabolomics and Proteomics Analysis to Discover Signatures of High-Grade Serous Ovarian Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12113447
Abstract: Simple Summary In-time diagnosing ovarian cancer, intractable cancer that has no symptoms can increase the survival of women. The aim of this study was to discover biomarkers from liquid biopsy samples using multi-omics approach, metabolomics… read more here.
Keywords: metabolomics proteomics; analysis; discover; convergence plasma ... See more keywords
Preclinical and Clinical Applications of Metabolomics and Proteomics in Glioblastoma Research
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010348
Abstract: Glioblastoma (GB) is a primary malignancy of the central nervous system that is classified by the WHO as a grade IV astrocytoma. Despite decades of research, several aspects about the biology of GB are still… read more here.
Keywords: preclinical clinical; clinical applications; applications metabolomics; proteomics glioblastoma ... See more keywords
Qualitative and Quantitative Mass Spectrometry in Salivary Metabolomics and Proteomics
Sign Up to like & getrecommendations! Published in 2023 at "Metabolites"
DOI: 10.3390/metabo13020155
Abstract: The metabolomics and proteomics analysis of saliva, an excellent biofluid that is a rich source of biological compounds, allows for the safe and frequent screening of drugs, their metabolites, and molecular biomarkers of various diseases.… read more here.
Keywords: mass spectrometry; qualitative quantitative; spectrometry; metabolomics proteomics ... See more keywords