Clinical Value of Metagenomics Next-Generation Sequencing in Bronchoalveolar Lavage Fluid for Patients with Severe Hospital-Acquired Pneumonia: A Nested Case–Control Study
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s356662
Abstract: Background Metagenomics next-generation sequencing (mNGS) is more efficient in identifying pathogens responsible for pneumonia. However, whether these patients ultimately benefit from this improvement remains unknown. Methods In this retrospective, nested, case–control study, patients with severe… read more here.
Keywords: metagenomics next; generation sequencing; next generation; day ... See more keywords
Chronic Splenic Melioidosis in a Patient with Fever of Unknown Origin Diagnosed by Metagenomics Next-Generation Sequencing: An Emerging Cause and Literature Review
Sign Up to like & getrecommendations! Published in 2023 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s406358
Abstract: Introduction Human melioidosis is an emerging infectious disease in tropical areas of China, and chronic melioidosis can be a rare cause of fever of unknown origin (FUO). Timely diagnosis may improve the prognosis of melioidosis.… read more here.
Keywords: unknown origin; fever unknown; metagenomics next; generation sequencing ... See more keywords
Analysis of Negative Results of Metagenomics Next-Generation Sequencing in Clinical Practice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.892076
Abstract: Background Metagenomics next-generation sequencing (mNGS) has been increasingly used in the clinic, which provides a powerful tool for the etiological diagnosis of infectious diseases. Precise treatment can be carried out according to the positive mNGS… read more here.
Keywords: negative results; metagenomics next; clinical practice; next generation ... See more keywords
Case Report: Metagenomics Next-Generation Sequencing for Diagnosing Cerebral Infarction and Infection Caused by Hematogenous Disseminated Mucormycosis in a Patient With Acute Lymphoblastic Leukemia
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.779981
Abstract: Disseminated mucormycosis, a serious complication, is associated with high mortality in patients with acute leukemia after chemotherapy. Blood cultures are always negative because of recurrent empirical antifungal treatments. The identification of pathogens is important for… read more here.
Keywords: case report; metagenomics next; next generation; mucormycosis ... See more keywords