Chlorodifluoromethane-triggered formation of difluoromethylated arenes catalysed by palladium.
Sign Up to like & getrecommendations! Published in 2017 at "Nature chemistry"
DOI: 10.1038/nchem.2746
Abstract: Difluoromethylated aromatic compounds are of increasing importance in pharmaceuticals, agrochemicals and materials. Chlorodifluoromethane (ClCF2H), an inexpensive, abundant and widely used industrial raw material, represents the ideal and most straightforward difluoromethylating reagent, but introduction of the… read more here.
Keywords: triggered formation; difluoromethylated arenes; chlorodifluoromethane triggered; metal difluorocarbene ... See more keywords
Transition-metal difluorocarbene complexes.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc04029d
Abstract: Although transition metal carbenes have found widespread applications and difluorocarbene has served as a versatile intermediate, it is still quite challenging to make use of transition-metal difluorocarbenes in synthetic chemistry due to their unpredictable reactivities.… read more here.
Keywords: metal; difluorocarbene complexes; metal difluorocarbene; transition metal ... See more keywords