Metal NHC Complexes with Naphthalimide Ligands as DNA‐Interacting Antiproliferative Agents
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DOI: 10.1002/cmdc.201600557
Abstract: Naphthalimide‐based N‐heterocyclic carbene (NHC) complexes of the type [(1,5‐cyclooctadiene)(NHC)RhCl)] (4 a–c), [(p‐cymene)(NHC)RuCl2)] (5 a–c), and [(NHC)CuBr] (6 a–c) were synthesized and investigated as antiproliferative agents that target DNA. The cytotoxic effects were largely driven by the naphthalimide structure,… read more here.
Keywords: metal nhc; complexes naphthalimide; antiproliferative agents; ligands dna ... See more keywords
Ester Hydrogenation with Bifunctional Metal–NHC Catalysts: Recent Advances
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DOI: 10.1021/acsomega.0c04819
Abstract: Hydrogenation of ester to alcohol is an essential reaction in organic chemistry due to its importance in the production of a wide range of bulk and fine chemicals. There are a number of homogeneous and… read more here.
Keywords: metal nhc; ester hydrogenation; metal; recent advances ... See more keywords
Destruction of chemical warfare agent simulants by air and moisture stable metal NHC complexes.
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DOI: 10.1039/c7dt04805j
Abstract: The cooperative effect of both NHC and metal centre has been found to destroy chemical warfare agent (CWA) simulants. Choice of both the metal and NHC is key to these transformations as simple, monodentate N-heterocyclic… read more here.
Keywords: metal nhc; warfare agent; metal; chemical warfare ... See more keywords
Different effects of metal-NHC bond cleavage on the Pd/NHC and Ni/NHC catalyzed α-arylation of ketones with aryl halides
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DOI: 10.1039/d0qi01411g
Abstract: Recently, the dynamic nature of the metal-NHC bond has been proposed and the key role of chemical evolution in changing the nature of catalytically active sites is now an emerging topic. A comparative analysis of… read more here.
Keywords: cleavage; aryl halides; nhc bond; arylation ... See more keywords