Metal- and solvent-free, iodine-catalyzed cyclocondensation and CH bond sulphenylation: A facile access to C-4 sulfenylated pyrazoles via a domino multicomponent reaction
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DOI: 10.1016/j.tet.2017.02.046
Abstract: Abstract We describe herein a green and efficient MCRs protocol to synthesize C-4 sulfenylated pyrazoles by iodine-catalyzed cyclocondensation and direct C H bond sulphenylation reactions. Through this protocol, two new C N bonds and one… read more here.
Keywords: iodine catalyzed; bond sulphenylation; bond; metal solvent ... See more keywords
Metal- and solvent-free synthesis of amides using substitute formamides as an amino source under mild conditions
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DOI: 10.1038/s41598-019-39240-z
Abstract: This study described an efficient and practical approach for amide synthesis. The reaction was conducted under metal- and solvent-free conditions at a mild temperature (40 °C) in air, and readily available formamides were used as an… read more here.
Keywords: metal solvent; solvent free; free synthesis; amino source ... See more keywords
Brønsted acid-catalyzed metal- and solvent-free quinoline synthesis from N-alkyl anilines and alkynes or alkenes
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DOI: 10.1039/c7gc03175k
Abstract: Bronsted acid-catalyzed cyclization reactions of N-alkyl anilines with alkynes or alkenes in the presence of oxygen gas as an oxidant under metal- and solvent-free conditions are described. Various quinoline derivatives are obtained in satisfactory to… read more here.
Keywords: alkynes alkenes; alkyl anilines; metal solvent; acid catalyzed ... See more keywords
Metal- and solvent-free synthesis of aminoalcohols under continuous flow conditions
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DOI: 10.1039/c9re00396g
Abstract: The use of multifunctional organocatalysts and continuous flow platforms are commonplace in modern chemical transformation. Herein, we describe a method for immobilization of trifunctional organocatalysts on porous composite hollow fibers and demonstrate their application as… read more here.
Keywords: metal solvent; chemical transformation; trifunctional organocatalysts; continuous flow ... See more keywords