Accessing aliphatic alcohols for metallaphotoredox catalyzed C(sp3)-arylation
Sign Up to like & getrecommendations! Published in 2021 at "Chem"
DOI: 10.1016/j.chempr.2021.09.006
Abstract: Common cross-coupling reactions to obtain C(sp2)–C(sp3)-bonds are hampered by the abundance of nucleophilic and electrophilic functional groups. Recently in Nature, Dong and MacMillan developed a mild activation of a diverse range of alcohols with an… read more here.
Keywords: aliphatic alcohols; catalyzed sp3; arylation; metallaphotoredox catalyzed ... See more keywords
Palladium Metallaphotoredox-Catalyzed 2-Arylation of Indole Derivatives.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01674
Abstract: Given that biaryl motifs are found in many useful molecules, including pesticides, pharmaceuticals, functional materials, and polymers, the development of methods for their construction is important. Herein, we report a two-step method for C(sp2)-H/C(sp2)-H cross-coupling… read more here.
Keywords: metallaphotoredox catalyzed; arylation indole; indole derivatives; catalyzed arylation ... See more keywords
Metallaphotoredox-catalyzed C–H activation: regio-selective annulation of allenes with benzamide
Sign Up to like & getrecommendations! Published in 2021 at "Organic chemistry frontiers"
DOI: 10.1039/d0qo01127d
Abstract: We have developed an efficient annulation of benzamides with allenes using cobalt and photoredox dual catalysis under an oxygen atmosphere. This reaction provides a mild and environmentally friendly method for the construction of isoquinolinone scaffolds… read more here.
Keywords: annulation; metallaphotoredox catalyzed; catalyzed activation; regio selective ... See more keywords
Palladium metallaphotoredox-catalyzed 3-acylation of indole derivatives.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03658d
Abstract: 3-Acylindole motifs are wildly found in pharmaceuticals and biologically active alkaloids. Synthesis of this motif from aldehydes and indoles via dehydrogenative cross-coupling (CDC) reactions is the most efficient pathway. Here, we report a method for… read more here.
Keywords: metallaphotoredox catalyzed; acylation indole; indole derivatives; catalyzed acylation ... See more keywords