NMR backbone resonance assignment of New Delhi metallo-beta-lactamase
Sign Up to like & getrecommendations! Published in 2017 at "Biomolecular NMR Assignments"
DOI: 10.1007/s12104-017-9756-5
Abstract: The emerging of the New Delhi metallo-beta-lactamase (NDM-1) has become one of the greatest threats to the clinical treatment. Although the structure of NDM-1 has been determined by X-ray crystallography, the molecular mechanism and process… read more here.
Keywords: new delhi; beta lactamase; metallo beta; spectroscopy ... See more keywords
Frequency Distribution, Genotypes and the most Prevalent Sequence Types of New Delhi Metallo-beta-lactamase-Producing Escherichia coli among Clinical Isolates around the World; A Review.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2019.06.008
Abstract: BACKGROUND AND AIM New Delhi Metallo-beta-lactamase (NDM)-producing Escherichia coli (E. coli) is allegedly perceived as one of the primary multidrug-resistant bacteria causing infections in hospitals and clinics. In this paper we present the frequency distribution,… read more here.
Keywords: new delhi; beta lactamase; coli; metallo beta ... See more keywords
Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical Candidates.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c00766
Abstract: With the emergence and rapid spreading of NDM-1 and existence of clinically relevant VIM-1 and IMP-1, discovery of pan inhibitors targeting metallo-beta-lactamases (MBLs) became critical in our battle against bacterial infection. Concurrent with our fragment… read more here.
Keywords: beta; chemistry; beta lactamase; lactamase inhibitors ... See more keywords
High prevalence of imipenem-resistant and metallo-beta-lactamase-producing Pseudomonas aeruginosa in the Burns Hospital in Tunisia: detection of a novel class 1 integron
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Chemotherapy"
DOI: 10.1080/1120009x.2019.1582168
Abstract: Pseudomonas aeruginosa is one of the most important causes of nosocomial infections, and its eradication is very difficult due to its multidrug resistance. The objective of the present study was to characterize the metallo-beta-lactamases (MBLs),… read more here.
Keywords: metallo beta; imipenem resistant; class integron; class ... See more keywords
The in vitro and in vivo potential of metal-chelating agents as metallo-beta-lactamase inhibitors against carbapenem-resistant Enterobacterales.
Sign Up to like & getrecommendations! Published in 2022 at "FEMS microbiology letters"
DOI: 10.1093/femsle/fnac122
Abstract: The recent surge in beta-lactamase resistance has created superbugs which pose a current and significant threat to public healthcare. This has created an urgent need to keep pace with the discovery of inhibitors that can… read more here.
Keywords: vitro vivo; carbapenem resistant; beta lactamase; metallo beta ... See more keywords
Aztreonam-Avibactam Susceptibility Testing Program for Metallo-Beta-Lactamase-Producing Enterobacterales in the Antibiotic Resistance Laboratory Network, March 2019 to December 2020
Sign Up to like & getrecommendations! Published in 2021 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00486-21
Abstract: Aztreonam-avibactam is a drug combination pending phase 3 clinical trials and is suggested for treatment of severe infections caused by metallo-beta-lactamase (MBL)-producing Enterobacterales by combining ceftazidime-avibactam and aztreonam. Beginning in 2019, four Antibiotic Resistance Laboratory… read more here.
Keywords: producing enterobacterales; metallo beta; aztreonam avibactam; resistance laboratory ... See more keywords
A hospital based surveillance of metallo-beta-lactamase producing gram negative bacteria in Nepal by imipenem-EDTA disk method
Sign Up to like & getrecommendations! Published in 2017 at "BMC Research Notes"
DOI: 10.1186/s13104-017-2640-7
Abstract: BackgroundA rising threat of the rapid spread of acquired metallo-beta-lactamases (MBLs) among major Gram-negative pathogens is a matter of public health concern worldwide. Hence, for a low income nation like Nepal, surveillance data on MBL… read more here.
Keywords: mbl production; gram negative; metallo beta; surveillance ... See more keywords
Identification of São Paulo metallo-beta-lactamase-1-producing Pseudomonas aeruginosa in the Central-West region of Brazil: a case study.
Sign Up to like & getrecommendations! Published in 2017 at "Revista da Sociedade Brasileira de Medicina Tropical"
DOI: 10.1590/0037-8682-0284-2016
Abstract: Metallo-beta-lactamase production is an important mechanism for carbapenem resistance of Pseudomonas aeruginosa , which represents an emerging public health challenge. We report the case of a patient admitted to an intensive care unit, with sepsis… read more here.
Keywords: beta lactamase; metallo beta; case;
Molecular detection of Metallo-Beta-Lactamase and alginate in multidrug resistance Pseudomonas aeruginosa isolated from the clinical specimen
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medicine and Life"
DOI: 10.25122/jml-2021-0196
Abstract: Pseudomonas aeruginosa pathogen is opportunistic. Several virulence factors and biofilms can cause its pathogenicity. Furthermore, infections triggered via multidrug-resistant P. aeruginosa among hospitalized patients are a public health concern. The primary antimicrobial agents in treating… read more here.
Keywords: clinical isolates; pseudomonas aeruginosa; multidrug resistance; beta lactamase ... See more keywords
Increased Risk of Acquisition of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) among a Cohort of COVID-19 Patients in a Teaching Hospital in Tuscany, Italy
Sign Up to like & getrecommendations! Published in 2020 at "Pathogens"
DOI: 10.3390/pathogens9080635
Abstract: We describe the epidemiology of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) colonization/infection in a cohort of COVID-19 patients in an Italian teaching hospital. These patients had an increased risk of NDM-CRE acquisition versus the usual… read more here.
Keywords: ndm cre; new delhi; beta lactamase; metallo beta ... See more keywords