Cloning and Expression of a Metalloprotease Gene from Morganella morganii Strain ZM
Sign Up to like & getrecommendations! Published in 2017 at "BioNanoScience"
DOI: 10.1007/s12668-017-0439-6
Abstract: Morganella morganii is an opportunistic pathogen which causes a wide range of clinical infections. It is well known that metalloproteases synthesized by pathogenic microorganisms play an important role as virulence factors. In this work, we… read more here.
Keywords: morganella morganii; metalloprotease; morganii strain; gene ... See more keywords
Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.09.019
Abstract: In higher vertebrates, cephalic neural crest cells (NCCs) form craniofacial skeleton by differentiating into chondrocytes and osteoblasts. A subpopulation of cephalic NCCs, cardiac NCCs (CNCCs), migrates to the heart. However, CNCCs mostly do not yield… read more here.
Keywords: metalloprotease dependent; bmp; metalloprotease; fate ... See more keywords
Pharmacophore modeling coupled with molecular dynamic simulation approach to identify new leads for meprin-β metalloprotease
Sign Up to like & getrecommendations! Published in 2019 at "Computational biology and chemistry"
DOI: 10.1016/j.compbiolchem.2019.04.014
Abstract: Human meprin beta metalloprotease, a small subgroup of the astacin family, is a potent drug target for the treatment of several disorders such as fibrosis, neurodegenerative disease in particular Alzheimer and inflammatory bowel diseases. In… read more here.
Keywords: modeling coupled; metalloprotease; pharmacophore modeling; molecular dynamic ... See more keywords
Enhancement of Z-aspartame synthesis by rational engineering of metalloprotease.
Sign Up to like & getrecommendations! Published in 2018 at "Food chemistry"
DOI: 10.1016/j.foodchem.2018.01.108
Abstract: Metalloprotease PT121Y114S, an effective catalyst for Z-aspartame synthesis under the substrate (Z-Asp:l-Phe-OMe) molar ratio of 1:5, was obtained previously. Herein, a computational strategy combining molecular dynamics simulation of the enzyme-substrate complex with binding free energy… read more here.
Keywords: phe ome; aspartame synthesis; metalloprotease; pt121y114s ... See more keywords
Eco-friendly enzymatic dehairing of goatskins utilizing a metalloprotease high-effectively expressed by Bacillus subtilis SCK6
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cleaner Production"
DOI: 10.1016/j.jclepro.2018.12.084
Abstract: Abstract In this study, an extracellular metalloprotease (EMPr) from Bacillus sp. LCB14 was cloned, successfully expressed in Bacillus subtilis SCK6, and utilized to dehair goat skins in leather-making processes. Through optimization of fermentation conditions, the… read more here.
Keywords: bacillus subtilis; metalloprotease; expressed bacillus; empr ... See more keywords
Deep profiling of the cleavage specificity and human substrates of snake venom metalloprotease HF3 by PICS using proteome derived peptide libraries and TAILS N-terminomics.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.9b00325
Abstract: Snakebite is a major medical concern in many parts of the world with metalloproteases playing important roles in the pathological effects of Viperidae venoms, including local tissue damage, hemorrhage and coagulopathy. Hemorrhagic Factor 3 (HF3),… read more here.
Keywords: hf3; cleavage; metalloprotease; cleavage sites ... See more keywords
Regulation of the trafficking and the function of the metalloprotease ADAM10 by tetraspanins.
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DOI: 10.1042/bst20160296
Abstract: By interacting directly with partner proteins and with one another, tetraspanins organize a network of interactions referred to as the tetraspanin web. ADAM10 (A Disintegrin And Metalloprotease 10), an essential membrane-anchored metalloprotease that cleaves off… read more here.
Keywords: adam10; trafficking function; metalloprotease; function metalloprotease ... See more keywords
Plasma matrix metalloprotease 9 correlates with blood lymphocytosis, leukemic cell invasiveness, and prognosis in B-cell chronic lymphocytic leukemia
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DOI: 10.1177/1010428317694325
Abstract: The complex biology underlying chronic lymphocytic leukemia cell migration and tissue invasiveness is not yet completely understood and might provide novel predictive markers and therapeutic targets. A total of 36 patients out of treatment from… read more here.
Keywords: metalloprotease; matrix metalloprotease; biology; chronic lymphocytic ... See more keywords
Relationship between Metalloprotease-7 and -14 and Tissue Inhibitor of Metalloprotease 1 Expression by Mucosal Stromal Cells and Colorectal Cancer Development in Inflammatory Bowel Disease
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DOI: 10.3390/biomedicines9050495
Abstract: Colorectal carcinoma (CRC) associated with inflammatory bowel disease (IBD) is an example of an inflammation-related cancer. Matrix metalloproteases (MMP) are known to be associated with both processes. The aim of the study was to compare… read more here.
Keywords: metalloprotease; tissue; expression; associated crc ... See more keywords
CsCIPK11-Regulated Metalloprotease CsFtsH5 Mediates the Cold Response of Tea Plants
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24076288
Abstract: Photosystem II repair in chloroplasts is a critical process involved in maintaining a plant’s photosynthetic activity under cold stress. FtsH (filamentation temperature-sensitive H) is an essential metalloprotease that is required for chloroplast photosystem II repair.… read more here.
Keywords: metalloprotease; cold stress; tea; csftsh5 ... See more keywords
The M35 Metalloprotease Effector FocM35_1 Is Required for Full Virulence of Fusarium oxysporum f. sp. cubense Tropical Race 4
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DOI: 10.3390/pathogens10060670
Abstract: Fusarium oxysporum f. sp. cubense tropical race 4 (Foc TR4) causes Fusarium wilt of banana, the most devastating disease on a banana plant. The genome of Foc TR4 encodes many candidate effector proteins. However, little… read more here.
Keywords: virulence; foc tr4; focm35; metalloprotease ... See more keywords