Incremental prognostic value of biomarkers in PARADIGM-HF.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of heart failure"
DOI: 10.1002/ejhf.2887
Abstract: BACKGROUND It is uncertain how much candidate biomarkers improve risk prediction when added to comprehensive models including routinely collected clinical and laboratory variables in heart failure. METHODS Aldosterone, cystatin C, high sensitivity-troponin T (hs-TnT), galectin-3,… read more here.
Keywords: laboratory; value biomarkers; incremental prognostic; biomarkers paradigm ... See more keywords
The regulation of trophoblast invasion and decidual reaction by matrix metalloproteinase‐2, metalloproteinase‐7, and metalloproteinase‐9 expressions in the rat endometrium
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive Medicine and Biology"
DOI: 10.1002/rmb2.12342
Abstract: We aimed to evaluate how matrix metalloproteinases (MMPs) regulate the trophoblast invasion and placentation. read more here.
Keywords: trophoblast invasion; metalloproteinase; matrix; metalloproteinase metalloproteinase ... See more keywords
The Natural Ligand for Metalloproteinase-A Multifaceted Drug Target
Sign Up to like & getrecommendations! Published in 2022 at "Applied Biochemistry and Biotechnology"
DOI: 10.1007/s12010-021-03778-4
Abstract: Metalloproteinase is one of the key components of Russell viper venom and it is the root cause of edema, blood coagulation, local tissue damage, hemorrhage, and inflammation during snakebite envenoming. Hence, finding a suitable metalloproteinase… read more here.
Keywords: metalloproteinase; multifaceted drug; metalloproteinase multifaceted; drug ... See more keywords
Biochemical, pharmacological and structural characterization of BmooMP-I, a new P-I metalloproteinase from Bothrops moojeni venom.
Sign Up to like & getrecommendations! Published in 2020 at "Biochimie"
DOI: 10.1016/j.biochi.2020.09.001
Abstract: Snakebite envenoming is still a worrying health problem in countries under development, being recognized as a neglected disease by the World Health Organization. In Latin America, snakes from the genus Bothrops are widely spread and… read more here.
Keywords: bmoomp new; pharmacological structural; moojeni venom; metalloproteinase ... See more keywords
Local and systemic effects of BtaMP-1, a new weakly hemorrhagic snake venom metalloproteinase purified from Bothriopsis taeniata snake venom.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.09.032
Abstract: A new weak hemorrhagic metalloproteinase named BtaMP-1 was purified from Bothriopsis taeniata snake venom by molecular exclusion followed by anion exchange chromatographies. This protein showed a molecular mass of 25,968.16 Da and is composed of 218… read more here.
Keywords: purified bothriopsis; bothriopsis taeniata; metalloproteinase; taeniata snake ... See more keywords
HPLC-MS/MS method optimisation for matrix metalloproteinase 3 and matrix metalloproteinase 9 determination in human blood serum using target analysis.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2017.11.067
Abstract: A quantitative analysis of zinc endopeptidases matrix metalloproteinase 9 (MMP9) and matrix metalloproteinase 3 (MMP3) from human blood serum are presented. Both matrix metalloproteinases (MMP) are present in human blood serum and can be used… read more here.
Keywords: matrix metalloproteinase; analysis; metalloproteinase; blood serum ... See more keywords
First trimester serum matrix metalloproteinase-7 is a poor predictor of late-onset preeclampsia.
Sign Up to like & getrecommendations! Published in 2022 at "Pregnancy hypertension"
DOI: 10.1016/j.preghy.2022.03.002
Abstract: OBJECTIVES This study aims to evaluate matrix metalloproteinase-7 as a first trimester biomarker for late-onset preeclampsia, both alone and in combination with mean arterial pressure, uterine artery pulsatility index, and maternal characteristics. STUDY DESIGN We… read more here.
Keywords: onset preeclampsia; metalloproteinase; late onset; matrix metalloproteinase ... See more keywords
Tissue Inhibitor of Metalloproteinase (TIMP) Peptidomimetic as an Adjunctive Therapy for Infectious Keratitis.
Sign Up to like & getrecommendations! Published in 2020 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.0c01473
Abstract: Matrix metalloproteinase 9 (MMP-9) has a key role in many biological processes, and while it is crucial for a normal immune response, excessive release of this enzyme can lead to severe tissue damage, as evidenced… read more here.
Keywords: infectious keratitis; metalloproteinase; timp peptidomimetic; tissue ... See more keywords
Relationships of Matrix Metalloproteinase 1 and a Tissue Inhibitor of Metalloproteinase to Collagen Metabolism in Haliotis discus hannai.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c05931
Abstract: In response to physical, chemical, and/or biological stimuli, considerable tissue self-degradation occurs in abalone, causing severe post-harvest quality loss. During this process, the extracellular matrix (ECM) is greatly degraded by endogenous proteases. The main component… read more here.
Keywords: tissue self; collagen; self degradation; activity ... See more keywords
Functionalized Hyaluronic Acid for “In Situ” Matrix Metalloproteinase Inhibition: A Bioactive Material to Treat the Dry Eye Sydrome
Sign Up to like & getrecommendations! Published in 2022 at "ACS Macro Letters"
DOI: 10.1021/acsmacrolett.2c00455
Abstract: Hyaluronic acid (HA) is a naturally occurring polysaccharide with many molecular functions, including maintaining the structure and physiology of the tissues, tissue remodeling, and inflammation. HA is found naturally in physiological tear fluid, possesses excellent… read more here.
Keywords: metalloproteinase; dry eye; hyaluronic acid; material ... See more keywords
Bronchial epithelium repair by Esculentin-1a-derived antimicrobial peptides: involvement of metalloproteinase-9 and interleukin-8, and evaluation of peptides’ immunogenicity
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-55426-x
Abstract: The airway epithelium is seriously damaged upon pulmonary Pseudomonas aeruginosa infection, especially in cystic fibrosis (CF) sufferers. Therefore, the discovery of novel anti-infective agents accelerating healing of infected injured tissues is crucial. The antipseudomonal peptides… read more here.
Keywords: epithelium repair; epithelium; metalloproteinase; esc peptides ... See more keywords