Non‐immunological toxicological mechanisms of metamizole‐associated neutropenia in HL60 cells
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DOI: 10.1016/j.bcp.2019.01.011
Abstract: Graphical abstract Figure. No caption available. &NA; Metamizole is an analgesic and antipyretic, but can cause neutropenia and agranulocytosis. We investigated the toxicity of the metabolites N‐methyl‐4‐aminoantipyrine (MAA), 4‐aminoantipyrine (AA), N‐formyl‐4‐aminoantipyrine (FAA) and N‐acetyl‐4‐aminoantipyrine (AAA)… read more here.
Keywords: metamizole associated; aminoantipyrine; hemin; hl60 cells ... See more keywords