Metastasis associated long noncoding RNAs in glioblastoma: Biomarkers and therapeutic targets.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cellular physiology"
DOI: 10.1002/jcp.30577
Abstract: Glioblastoma (GBM) is the most aggressive, malignant, and therapeutically challenging Grade IV tumor of the brain. Although the possibility of distant metastasis is extremely rare, GBM is known to cause intracranial metastasis forming aggressive secondary lesions… read more here.
Keywords: long noncoding; glioblastoma; therapeutic targets; metastasis ... See more keywords
Loss of Caveolin-1 in Metastasis-Associated Macrophages Drives Lung Metastatic Growth through Increased Angiogenesis
Sign Up to like & getrecommendations! Published in 2017 at "Cell Reports"
DOI: 10.1016/j.celrep.2017.11.034
Abstract: Summary Although it is well established that tumor-associated macrophages take part in each step of cancer progression, less is known about the distinct role of the so-called metastasis-associated macrophages (MAMs) at the metastatic site. Previous… read more here.
Keywords: metastasis; cav1; associated macrophages; growth ... See more keywords
Isolation and characterization of patient-derived CNS metastasis-associated stromal cell lines
Sign Up to like & getrecommendations! Published in 2019 at "Oncogene"
DOI: 10.1038/s41388-019-0680-2
Abstract: The functional role of human derived stromal cells in the tumor microenviornment of CNS metastases (CM) remain understudied. The purpose of the current study was to isolate and characterize stromal cells of the tumor microenvironment… read more here.
Keywords: cns metastasis; metastasis associated; associated stromal; cell lines ... See more keywords
Metastasis-Associated Protein 1 Is Involved in Angiogenesis after Transarterial Chemoembolization Treatment
Sign Up to like & getrecommendations! Published in 2017 at "BioMed Research International"
DOI: 10.1155/2017/6757898
Abstract: Background Transarterial chemoembolization (TACE), a well-established treatment for unresectable hepatocellular carcinoma (HCC), blocks the arterial blood supply to the tumor, which can be short-lived as development of collateral neovessels, leading to the failure of treatment.… read more here.
Keywords: associated protein; angiogenesis; treatment; transarterial chemoembolization ... See more keywords
Abstract 4620: Signaling cascade of metastasis-associated macrophages determines breast cancer distal metastasis
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-4620
Abstract: Macrophages are abundantly found in the tumor microenvironment and enhance malignancy. At distal metastatic sites, our previous studies identified a distinct population of metastasis-associated macrophages (MAMs) that promote tumor cell extravasation, seeding and persistent growth.… read more here.
Keywords: flt1; breast cancer; metastasis; cancer ... See more keywords
Role of metastasis-associated protein 1 in prognosis of patients with digestive tract cancers: A meta-analysis
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0176431
Abstract: Objectives Metastasis-associated protein 1 (MTA1) is a transcriptional regulator and significantly associated with prognosis of patients with cancer. However, its role as a potential prognostic marker in digestive tract cancer (DTC) is controversial. In this… read more here.
Keywords: associated protein; metastasis; digestive tract; metastasis associated ... See more keywords
Analysis of the regulation of metastasis-associated lung adenocarcinoma transcript 1 on the biological behavior of breast cancer
Sign Up to like & getrecommendations! Published in 2021 at "Translational Cancer Research"
DOI: 10.21037/tcr-20-3221
Abstract: Background Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a class of long non-coding RNA (lncRNA) that has been proved to be closely related to many cancers. Methods The relevant research on MALAT1 in cancers published… read more here.
Keywords: cancer; analysis; malat1; breast cancer ... See more keywords
Silencing of LncRNA Metastasis-Associated Lung Adenocarcinoma Transcript 1 Inhibits the Proliferation and Promotes the Apoptosis of Gastric Cancer Cells Through Regulating microRNA-22-3p-Mediated ErbB3
Sign Up to like & getrecommendations! Published in 2020 at "OncoTargets and therapy"
DOI: 10.2147/ott.s222375
Abstract: Purpose This study aimed to investigate the regulatory effects and mechanisms of long non-coding RNA (LncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) on gastric cancer (GC) cells. Methods The expression of MALAT1 was detected in… read more here.
Keywords: associated lung; malat1; lung adenocarcinoma; metastasis associated ... See more keywords
β2-Adrenergic Signalling Promotes Cell Migration by Upregulating Expression of the Metastasis-Associated Molecule LYPD3
Sign Up to like & getrecommendations! Published in 2020 at "Biology"
DOI: 10.3390/biology9020039
Abstract: Metastasis is associated with poor prognosis in breast cancer. Although some studies suggest beta-blockers increase survival by delaying metastasis, others have been discordant. This study provides both insights into the anomalous findings and identifies potential… read more here.
Keywords: breast; metastasis; expression; cancer ... See more keywords
Identification of a Novel Renal Metastasis Associated CpG-Based DNA Methylation Signature (RMAMS)
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911190
Abstract: Approximately 21% of patients with renal cell cancer (RCC) present with synchronous metastatic disease at the time of diagnosis, and metachronous metastatic disease occurs in 20–50% of cases within 5 years. Recent advances in adjuvant… read more here.
Keywords: methylation; metastasis associated; rcc; dna methylation ... See more keywords
Exploitation and Verification of a Stroma- and Metastasis-Associated Risk Prognostic Signature in Pancreatic Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15111336
Abstract: Pancreatic adenocarcinoma (PAAD), one of the most malignant tumors, not only has abundant mesenchymal components, but is also characterized by an extremely high metastatic risk. The purpose of this study was to construct a model… read more here.
Keywords: metastasis; metastasis associated; prognostic signature; pancreatic adenocarcinoma ... See more keywords