Up-regulation of Rho-associated kinase 1/2 by glucocorticoids promotes migration, invasion and metastasis of melanoma.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer letters"
DOI: 10.1016/j.canlet.2017.09.005
Abstract: Although glucocorticoids (GCs) regulate proliferation, differentiation and apoptosis of tumor cells, their influence on metastasis of tumor cells is poorly understood. Melanoma is a type of skin cancers with high metastasis. We investigated the effect… read more here.
Keywords: melanoma; metastasis melanoma; invasion; metastasis ... See more keywords
TIM-3 shuttled by MV3 cells-secreted exosomes inhibits CD4+ T cell immune function and induces macrophage M2 polarization to promote the growth and metastasis of melanoma cells
Sign Up to like & getrecommendations! Published in 2022 at "Translational Oncology"
DOI: 10.1016/j.tranon.2021.101334
Abstract: Highlights • MV3-Exo inhibits CD4+ t cell immune function and induces M2-polarized macrophages.• TIM-3 is upregulated in MV3 cells-secreted exosomes.• TIM-3 inhibits CD4+ t cell immune function and induces M2-polarized macrophages.• TIM-3 shuttled by MV3-Exo… read more here.
Keywords: function induces; immune function; cd4 cell; metastasis melanoma ... See more keywords
Ferroptosis Is Inhibited in Lymph, Promoting Metastasis of Melanoma.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-rw2020-128
Abstract: Lymphatic melanoma cells had less ferroptosis than cells injected intravenously or subcutaneously. read more here.
Keywords: inhibited lymph; lymph promoting; metastasis melanoma; melanoma ... See more keywords
Deciphering mechanisms of brain metastasis in melanoma - the gist of the matter
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Cancer"
DOI: 10.1186/s12943-018-0854-5
Abstract: Metastasis to distant organs and particularly the brain still represents the most serious obstacle in melanoma therapies. Melanoma cells acquire a phenotype to metastasize to the brain and successfully grow there through complex mechanisms determined… read more here.
Keywords: melanoma; metastasis melanoma; melanoma cells; brain metastasis ... See more keywords
TRPV4 Promotes Metastasis in Melanoma by Regulating Cell Motility through Cytoskeletal Rearrangement
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232315155
Abstract: The abnormal expression of Transient Receptor Potential cation channel subfamily V member 4 (TRPV4) is closely related to the progression of multiple tumors. In addition, TRPV4 is increasingly being considered a potential target for cancer… read more here.
Keywords: metastasis; trpv4 promotes; trpv4; promotes metastasis ... See more keywords
Imaging Assessment of Interval Metastasis from Melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12071033
Abstract: Interval metastasis is a particular metastatic category of metastatic localizations in the lymph nodes in patients with melanoma. Interval nodes are generally located at nonregional lymphatic stations placed along the pathway of the spread of… read more here.
Keywords: assessment interval; melanoma; imaging assessment; interval metastasis ... See more keywords