Hepatitis C virus core protein interacts with cellular metastasis suppressor Nm23-H1 and promotes cell migration and invasion
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Virology"
DOI: 10.1007/s00705-019-04151-x
Abstract: Hepatitis C virus (HCV) is the major etiological agent of hepatocellular carcinoma (HCC), which is the fourth most common cause of cancer-related deaths worldwide and second in terms of deaths of males (Bray et al.… read more here.
Keywords: protein; core protein; hcv; metastasis ... See more keywords
The Metastasis Suppressor Protein Nme1 Is a Concentration-Dependent Modulator of Ca2+/Calmodulin-Dependent Protein Kinase II.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry"
DOI: 10.1021/acs.biochem.9b00121
Abstract: Nucleoside diphosphate kinases (Nmes or NDPKs) have been implicated in a multitude of cellular processes, including an important role in metastasis suppression, and several enzymatic activities have been assigned to the Nme family. Nevertheless, for… read more here.
Keywords: protein; suppressor protein; metastasis suppressor; calmodulin dependent ... See more keywords
Computational analysis of the evolutionarily conserved Missing In Metastasis/Metastasis Suppressor 1 gene predicts novel interactions, regulatory regions and transcriptional control
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-40697-1
Abstract: Missing in Metastasis (MIM), or Metastasis Suppressor 1 (MTSS1), is a highly conserved protein, which links the plasma membrane to the actin cytoskeleton. MIM has been implicated in various cancers, however, its modes of action… read more here.
Keywords: mim; metastasis; computational analysis; missing metastasis ... See more keywords
A rare subpopulation of melanoma cells with low expression of metastasis suppressor NME1 is highly metastatic in vivo
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DOI: 10.1038/s41598-020-58996-3
Abstract: Despite recent advances in melanoma treatment, metastasis and resistance to therapy remain serious clinical challenges. NME1 is a metastasis suppressor, a class of proteins which inhibits metastatic spread of cancer cells without impact on growth… read more here.
Keywords: melanoma; rare subpopulation; metastasis; highly metastatic ... See more keywords
Identification of a novel metastasis inducing lncRNA which suppresses the KAI1/CD82 metastasis suppressor gene and is upregulated in triple-negative breast cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.18733
Abstract: Inactivation of tumor/metastasis suppressor genes via epigenetic silencing is a frequent event in human cancers. KAI1/CD82 is a metastasis suppressor gene whose normal protecting activity is deficient in twelve different solid malignancies. Here we have… read more here.
Keywords: metastasis; metastasis suppressor; breast cancer;
Re-Shaping the Pancreatic Cancer Tumor Microenvironment: A New Role for the Metastasis Suppressor NDRG1
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15102779
Abstract: Simple Summary Pancreatic cancer remains the leading cause of cancer death globally. With no reliable early detection strategy and limited treatment options, up to 90% of patients will lose their lives to this disease. In… read more here.
Keywords: metastasis suppressor; pancreatic cancer; tumor microenvironment; cancer tumor ... See more keywords