Cediranib phase II study in children with metastatic alveolar soft part sarcoma (ASPS).
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.10540
Abstract: 10540Background: ASPS, a rare, highly vascular sarcoma with a clinically indolent course, frequently presents with metastases at diagnosis. Standard sarcoma chemotherapy is ineffective. Vascular en... read more here.
Keywords: sarcoma; cediranib phase; metastatic alveolar; study children ... See more keywords
Activity and safety of crizotinib in patients with advanced, metastatic alveolar soft part sarcoma (ASPS) with rearrangement of TFE3: European Organization for Research and Treatment of Cancer (EORTC) phase 2 trial 90101 CREATE.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.11540
Abstract: 11540Background: ASPS is an orphan disease associated with rearrangement of transcription factor E3 (TFE3), leading to abnormal MET expression. We assessed crizotinib in pts with ASPS (NCT01524926)... read more here.
Keywords: advanced metastatic; metastatic alveolar; activity safety; safety crizotinib ... See more keywords