A mathematical model of the metastatic bottleneck predicts patient outcome and response to cancer treatment
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DOI: 10.1371/journal.pcbi.1008056
Abstract: Metastases are the main reason for cancer-related deaths. Initiation of metastases, where newly seeded tumor cells expand into colonies, presents a tremendous bottleneck to metastasis formation. Despite its importance, a quantitative description of metastasis initiation… read more here.
Keywords: patient outcome; model; bottleneck; metastatic bottleneck ... See more keywords