Silmitasertib plus gemcitabine and cisplatin first‐line therapy in locally advanced/metastatic cholangiocarcinoma: A Phase 1b/2 study
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32804
Abstract: Background and Aims: This study aimed to investigate safety and efficacy of silmitasertib, an oral small molecule casein kinase 2 inhibitor, plus gemcitabine and cisplatin (G+C) versus G+C in locally advanced/metastatic cholangiocarcinoma. Approach and Results:… read more here.
Keywords: locally advanced; metastatic cholangiocarcinoma; advanced metastatic; study ... See more keywords
Aberrant Expression of Cell Cycle Regulator 14-3-3-σ and E-Cadherin in a Metastatic Cholangiocarcinoma in a Vervet Monkey (Chlorocebus pygerythrus).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of comparative pathology"
DOI: 10.1016/j.jcpa.2020.07.001
Abstract: We present a unique case of metastatic cholangiocarcinoma with concurrent abdominal cestodiasis in an African green monkey (Chlorocebus pygerythrus) that presented with respiratory insufficiency and abdominal discomfort. There were multiple white-grey masses in the liver… read more here.
Keywords: metastatic cholangiocarcinoma; cholangiocarcinoma; monkey chlorocebus; chlorocebus pygerythrus ... See more keywords
Case report: pembrolizumab-induced Type 1 diabetes in a patient with metastatic cholangiocarcinoma.
Sign Up to like & getrecommendations! Published in 2017 at "Immunotherapy"
DOI: 10.2217/imt-2017-0042
Abstract: BACKGROUND Immune checkpoint inhibitors are novel cancer therapies associated with numerous autoimmune toxicities, some of which are only now being appreciated. CASE PRESENTATION A 67-year old female with metastatic cholangiocarcinoma and no prior history of… read more here.
Keywords: metastatic cholangiocarcinoma; case; type diabetes; pembrolizumab ... See more keywords