Articles with "metastatic clear" as a keyword



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Survival Outcomes Associated With Cytoreductive Nephrectomy in Patients With Metastatic Clear Cell Renal Cell Carcinoma

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Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2022.12347

Abstract: Key Points Question Is cytoreductive nephrectomy associated with improved overall survival for patients with metastatic clear cell renal cell carcinoma? Findings In this cohort study of 12 766 patients, receipt of a cytoreductive nephrectomy was not… read more here.

Keywords: cell; survival; cytoreductive nephrectomy; metastatic clear ... See more keywords
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First-Line Systemic Therapy for Metastatic Clear-Cell Renal Cell Carcinoma: Critical Appraisal of Emerging Options

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Published in 2019 at "Targeted Oncology"

DOI: 10.1007/s11523-019-00676-y

Abstract: Until recently, a dichotomy existed in the front-line approach of metastatic clear-cell renal cell carcinoma (mRCC). Specifically, patients received either targeted therapy or immunotherapy. Targeted therapy entailed use of agents blocking signaling through the vascular… read more here.

Keywords: cell renal; renal cell; metastatic clear; therapy ... See more keywords
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Bone metastases and age are associated with earlier dose reductions in metastatic clear-cell renal cell carcinoma patients treated with angiogenesis inhibitors

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Published in 2018 at "Acta Clinica Belgica"

DOI: 10.1080/17843286.2018.1551744

Abstract: ABSTRACT Background: Metastatic clear-cell renal cell carcinoma (m-ccRCC) patients with bone metastases (BM) treated with vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors (TKI) have a poorer outcome compared to patients without BM. We… read more here.

Keywords: patients treated; age; dose reductions; metastatic clear ... See more keywords
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Soluble forms of PD-L1 and PD-1 as prognostic and predictive markers of sunitinib efficacy in patients with metastatic clear cell renal cell carcinoma

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Published in 2020 at "Oncoimmunology"

DOI: 10.1080/2162402x.2020.1846901

Abstract: ABSTRACT Metastatic clear cell renal cell carcinoma (mccRCC) benefits from several treatment options in the first-line setting with VEGFR inhibitors and/or immunotherapy including anti-PD-L1 or anti-PD1 agents. Identification of predictive biomarkers is highly needed to… read more here.

Keywords: levels spd; clear cell; spd spd; cell renal ... See more keywords
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Cardiac Involvement of Metastatic Clear Cell Sarcoma: A Multimodality Imaging Report

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Published in 2022 at "Circulation. Cardiovascular Imaging"

DOI: 10.1161/circimaging.121.013902

Abstract: Circ Cardiovasc Imaging. 2022;15:e013902. DOI: 10.1161/CIRCIMAGING.121.013902 May 2022 Correspondence to: Tommaso D’Angelo, MD, PhD (cand), Department of Biomedical Sciences and Morphological and Functional Imaging, University Hospital Messina, Italy; Department of Radiology and Nuclear Medicine, Erasmus… read more here.

Keywords: cell sarcoma; metastatic clear; sarcoma multimodality; clear cell ... See more keywords
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Metastatic Clear Cell Renal Cell Carcinoma Involving the Thyroid Gland: A Clinicopathologic Study of 17 Patients

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Published in 2022 at "International Journal of Surgical Pathology"

DOI: 10.1177/10668969221081729

Abstract: Background. Metastatic clear cell renal cell carcinoma (RCC) is one of the most common secondary thyroid malignancies. Diagnosis can be challenging, particularly if presenting many years after initial diagnosis. We reviewed clinicopathologic features and immunoprofile… read more here.

Keywords: cell renal; cell; thyroid gland; metastatic clear ... See more keywords
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Prognostic significance of ST6GalNAc-1 expression in patients with non-metastatic clear cell renal cell carcinoma

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Published in 2018 at "Oncotarget"

DOI: 10.18632/oncotarget.11258

Abstract: Background Sialyltransferase ST6GalNAc-1 is highly expressed in tumor cells and associated with tumor aggressiveness and poor prognosis. In the present study, we aimed to investigate the clinical and prognostic significance of sialyltransferase ST6GalNAc-1 in patients… read more here.

Keywords: patients non; metastatic clear; expression; cell ... See more keywords
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Patient-specific molecular alterations are associated with metastatic clear cell renal cell cancer progressing under tyrosine kinase inhibitor therapy

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Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.18200

Abstract: The availability of tyrosine kinase inhibitors (TKI) during the past ten years has led to improved response and overall survival of patients suffering from metastatic clear cell renal cell carcinoma (ccRCC). However, most of these… read more here.

Keywords: cell renal; metastatic clear; therapy; cell ... See more keywords
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Fat Loss in Patients with Metastatic Clear Cell Renal Cell Carcinoma Treated with Immune Checkpoint Inhibitors

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24043994

Abstract: The purpose of this study was to determine the prognostic impact of fat loss after immune checkpoint inhibitor (ICI) treatment in patients with metastatic clear cell renal cell carcinoma (ccRCC). Data from 60 patients treated… read more here.

Keywords: cell; immune checkpoint; loss; metastatic clear ... See more keywords