Opposing Roles of Vascular Endothelial Growth Factor C in Metastatic Dissemination and Resistance to Radio/Chemotherapy: Discussion of Mechanisms and Therapeutic Strategies.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-2217-9_1
Abstract: Many cancers can be cured by combining surgery with healthy margins, radiation therapy and chemotherapies. However, when the pathology becomes metastatic, cancers can be incurable. The best situation involves "chronicization" of the pathology even for… read more here.
Keywords: pathology; cancer cells; blood lymphatic; cancer ... See more keywords
Abstract A040: Multi-site sequencing of lethal prostate cancer reveals metastatic dissemination by independent and early-branching clones
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.prca2023-a040
Abstract: Primary prostate cancer (PCa) is frequently multifocal (genetically independent(GI) clones) and is further characterized by extensive intratumoral heterogeneity (genetically related clones). In metastatic castrate resistant PCa (mCRPC) monoclonal and polyclonal seeding of metastatic sites by… read more here.
Keywords: prostate cancer; metastatic dissemination; early branching; metastatic sites ... See more keywords
SEMA3C Depletion Promotes Neuroblastoma Metastatic Dissemination.
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DOI: 10.1158/2159-8290.cd-rw2017-198
Abstract: A neuroblastoma chick embryo xenograft model recapitulates tumor initiation and dissemination. read more here.
Keywords: neuroblastoma metastatic; metastatic dissemination; promotes neuroblastoma; sema3c depletion ... See more keywords
Ventricular metastatic dissemination of a paediatric craniopharyngioma: case report and literature review
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DOI: 10.3109/02688697.2016.1139050
Abstract: Abstract Distant intraventricular metastasis is extremely rare in childhood craniopharyngioma. Here, we report the isolated posterior ventricular recurrence of an adamantinomatous craniopharyngioma, in a child previously treated with surgery and proton beam therapy for local… read more here.
Keywords: metastatic dissemination; craniopharyngioma; paediatric craniopharyngioma; dissemination paediatric ... See more keywords
Inhibiting Endothelin Receptors with Macitentan Strengthens the Bone Protective Action of RANKL Inhibition and Reduces Metastatic Dissemination in Osteosarcoma
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DOI: 10.3390/cancers14071765
Abstract: Simple Summary The efficacy of current osteosarcoma therapy is diminished by two adverse events, namely resistance to chemotherapy and metastatic dissemination. In recent decades, research has been devoted to reducing these adverse events. Inhibiting bone… read more here.
Keywords: bone resorption; inhibition; dissemination; metastatic dissemination ... See more keywords