Efficacy and safety of recombinant human lymphotoxin‐α derivative with cisplatin and fluorouracil in patients with metastatic esophageal squamous cell carcinoma: A randomized, multicenter, open‐label, controlled, phase 2b trial
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DOI: 10.1002/cncr.30845
Abstract: Recombinant human lymphotoxin‐α derivative (rhLTα‐Da) is a lymphotoxin‐α derivative that is missing 27 N‐terminal amino acid residues. Previous studies indicated a benefit from the addition of rhLTα‐Da to cisplatin‐based treatment in patients with metastatic esophageal… read more here.
Keywords: recombinant human; lymphotoxin; metastatic esophageal; patients metastatic ... See more keywords
Real-World Treatment Patterns and Outcomes in Patients Receiving Second-Line Therapy for Advanced/Metastatic Esophageal Squamous Cell Carcinoma
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DOI: 10.1007/s12325-020-01394-y
Abstract: Introduction Currently available second-line (2L) therapies for advanced/metastatic esophageal squamous cell carcinoma (adv/met ESCC) include the taxanes paclitaxel and docetaxel. In clinical trials, such therapies have provided only modest improvements in survival. Few studies have… read more here.
Keywords: advanced metastatic; metastatic esophageal; patients receiving; adv met ... See more keywords
Comparison of intensity-modulated radiotherapy vs 3-dimensional conformal radiotherapy for patients with non-metastatic esophageal squamous cell carcinoma receiving definitive concurrent chemoradiotherapy
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DOI: 10.1097/md.0000000000010928
Abstract: Abstract Whether the survival outcome of patients with non-metastatic esophageal squamous cell carcinoma (NM-ESCC) receiving definitive concurrent chemoradiotherapy (CCRT) is better with intensity-modulated radiotherapy (IMRT) or with 3-dimensional conformal radiotherapy (3DCRT) has been debated in… read more here.
Keywords: esophageal; metastatic esophageal; patients non; radiotherapy ... See more keywords
Relationship between T stage and survival in distantly metastatic esophageal cancer
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DOI: 10.1097/md.0000000000020064
Abstract: Supplemental Digital Content is available in the text read more here.
Keywords: distantly metastatic; stage survival; esophageal cancer; relationship stage ... See more keywords
SEVERE DE NOVO PUSTULAR PSORIASIFORM IMMUNE-RELATED ADVERSE EVENT ASSOCIATED WITH NIVOLUMAB TREATMENT FOR METASTATIC ESOPHAGEAL ADENOCARCINOMA.
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DOI: 10.1111/cup.14185
Abstract: Breakthrough targeted therapies have produced significant improvements in survival for cancer patients, but have a propensity to cause cutaneous immune-related adverse events (irAEs). Psoriasiform irAEs, representing about 4% of dermatologic toxicities associated with immune checkpoint… read more here.
Keywords: ici therapy; immune related; psoriasiform; pustular psoriasiform ... See more keywords
Novel Treatment Options in Metastatic Esophageal Carcinoma: Checkpoint Inhibitors in Combination Therapies
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DOI: 10.1159/000527697
Abstract: Background: Metastatic esophageal carcinoma (EC) has a poor prognosis and only limited treatment options. While immune checkpoint inhibitors (ICIs) have improved the treatment of a broad spectrum of cancers, patients with EC mostly fail to… read more here.
Keywords: metastatic esophageal; combination; checkpoint; esophageal carcinoma ... See more keywords
Chemotherapy predictors and a time-dependent chemotherapy effect in metastatic esophageal cancer
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Gastrointestinal Oncology"
DOI: 10.4251/wjgo.v14.i2.511
Abstract: BACKGROUND Chemotherapy has long been shown to confer a survival benefit in patients with metastatic esophageal cancer. However, not all patients with metastatic disease receive chemotherapy. AIM To evaluate a large cancer database of metastatic… read more here.
Keywords: cancer; esophageal cancer; receiving chemotherapy; chemotherapy ... See more keywords