Efficacy and safety of recombinant human lymphotoxin‐α derivative with cisplatin and fluorouracil in patients with metastatic esophageal squamous cell carcinoma: A randomized, multicenter, open‐label, controlled, phase 2b trial
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DOI: 10.1002/cncr.30845
Abstract: Recombinant human lymphotoxin‐α derivative (rhLTα‐Da) is a lymphotoxin‐α derivative that is missing 27 N‐terminal amino acid residues. Previous studies indicated a benefit from the addition of rhLTα‐Da to cisplatin‐based treatment in patients with metastatic esophageal… read more here.
Keywords: recombinant human; lymphotoxin; metastatic esophageal; patients metastatic ... See more keywords
Real-World Treatment Patterns and Outcomes in Patients Receiving Second-Line Therapy for Advanced/Metastatic Esophageal Squamous Cell Carcinoma
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DOI: 10.1007/s12325-020-01394-y
Abstract: Introduction Currently available second-line (2L) therapies for advanced/metastatic esophageal squamous cell carcinoma (adv/met ESCC) include the taxanes paclitaxel and docetaxel. In clinical trials, such therapies have provided only modest improvements in survival. Few studies have… read more here.
Keywords: advanced metastatic; metastatic esophageal; patients receiving; adv met ... See more keywords
Comparison of intensity-modulated radiotherapy vs 3-dimensional conformal radiotherapy for patients with non-metastatic esophageal squamous cell carcinoma receiving definitive concurrent chemoradiotherapy
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DOI: 10.1097/md.0000000000010928
Abstract: Abstract Whether the survival outcome of patients with non-metastatic esophageal squamous cell carcinoma (NM-ESCC) receiving definitive concurrent chemoradiotherapy (CCRT) is better with intensity-modulated radiotherapy (IMRT) or with 3-dimensional conformal radiotherapy (3DCRT) has been debated in… read more here.
Keywords: esophageal; metastatic esophageal; patients non; radiotherapy ... See more keywords
Relationship between T stage and survival in distantly metastatic esophageal cancer
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DOI: 10.1097/md.0000000000020064
Abstract: Supplemental Digital Content is available in the text read more here.
Keywords: distantly metastatic; stage survival; esophageal cancer; relationship stage ... See more keywords
SEVERE DE NOVO PUSTULAR PSORIASIFORM IMMUNE-RELATED ADVERSE EVENT ASSOCIATED WITH NIVOLUMAB TREATMENT FOR METASTATIC ESOPHAGEAL ADENOCARCINOMA.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cutaneous pathology"
DOI: 10.1111/cup.14185
Abstract: Breakthrough targeted therapies have produced significant improvements in survival for cancer patients, but have a propensity to cause cutaneous immune-related adverse events (irAEs). Psoriasiform irAEs, representing about 4% of dermatologic toxicities associated with immune checkpoint… read more here.
Keywords: ici therapy; immune related; psoriasiform; pustular psoriasiform ... See more keywords
Novel Treatment Options in Metastatic Esophageal Carcinoma: Checkpoint Inhibitors in Combination Therapies
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DOI: 10.1159/000527697
Abstract: Background: Metastatic esophageal carcinoma (EC) has a poor prognosis and only limited treatment options. While immune checkpoint inhibitors (ICIs) have improved the treatment of a broad spectrum of cancers, patients with EC mostly fail to… read more here.
Keywords: metastatic esophageal; combination; checkpoint; esophageal carcinoma ... See more keywords
Consolidative thoracic radiotherapy improves the prognosis of metastatic esophageal cancer in the chemoimmunotherapy era: a propensity score matching study
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DOI: 10.1186/s12885-025-15118-4
Abstract: The role of consolidative thoracic radiotherapy in patients with metastatic esophageal cancer receiving chemotherapy combined with immunotherapy is unclear. This study aimed to evaluate the efficacy and safety of consolidative thoracic radiotherapy combined with chemotherapy… read more here.
Keywords: cancer; metastatic esophageal; group; consolidative thoracic ... See more keywords
The different prognostic factors between metastatic and nonmetastatic disease of esophageal neuroendocrine carcinoma.
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DOI: 10.4103/ijc.ijc_151_20
Abstract: PURPOSE The specific risk factors of metastatic and nonmetastatic esophageal neuroendocrine carcinoma (NEC) are still uncertain. Whether primary site surgery is necessary for all patients with esophageal NEC is unknown. METHODS Patients with esophageal NEC… read more here.
Keywords: metastatic esophageal; metastatic nonmetastatic; risk; esophageal ... See more keywords
Chemotherapy predictors and a time-dependent chemotherapy effect in metastatic esophageal cancer
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DOI: 10.4251/wjgo.v14.i2.511
Abstract: BACKGROUND Chemotherapy has long been shown to confer a survival benefit in patients with metastatic esophageal cancer. However, not all patients with metastatic disease receive chemotherapy. AIM To evaluate a large cancer database of metastatic… read more here.
Keywords: cancer; esophageal cancer; receiving chemotherapy; chemotherapy ... See more keywords