Articles with "metastatic high" as a keyword



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Pembrolizumab monotherapy in patients with previously treated metastatic high-grade neuroendocrine neoplasms: joint analysis of two prospective, non-randomised trials

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Published in 2020 at "British Journal of Cancer"

DOI: 10.1038/s41416-020-0775-0

Abstract: Background Metastatic high-grade neuroendocrine neoplasms (G3NENs) have limited treatment options after progression on platinum-based therapy. We addressed the role of Pembrolizumab in patients with previously treated metastatic G3NENs. Methods Two open-label, phase 2 studies enrolled… read more here.

Keywords: high grade; grade; patients previously; neuroendocrine neoplasms ... See more keywords
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Pembrolizumab (P) monotherapy in patients with previously treated metastatic high grade neuroendocrine neoplasms (HG-NENs).

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Published in 2018 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2018.36.15_suppl.4104

Abstract: 4104Background: There is currently no standard therapy for metastatic HG-NENs after progression on platinum based therapy and available chemotherapy is of limited benefit. Given the promising activ... read more here.

Keywords: patients previously; monotherapy patients; pembrolizumab monotherapy; treated metastatic ... See more keywords