Do locally advanced and metastatic human epithelial cancers evolve in ‘placental/decidual-like microenvironments’?
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DOI: 10.1007/s12094-018-1982-5
Abstract: Successful tumor microenvironments eventually kill the host. They are not only meant to nourish and protect tumor development, but to give them the right “soil” for perpetual malignant properties such as tissue invasion and metastasis.… read more here.
Keywords: advanced metastatic; epithelial cancers; human epithelial; cancers evolve ... See more keywords
Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers
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DOI: 10.1126/science.abl5447
Abstract: The accurate identification of antitumor T cell receptors (TCRs) represents a major challenge for the engineering of cell-based cancer immunotherapies. By mapping 55 neoantigen-specific TCR clonotypes (NeoTCRs) from 10 metastatic human tumors to their single-cell… read more here.
Keywords: cell; metastatic human; reactive cells; tumor ... See more keywords
Mechanisms Enhancing the Cytotoxic Effects of Bleomycin plus Suicide or Interferon-β Gene Lipofection in Metastatic Human Melanoma Cells.
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DOI: 10.2174/1871520618666180604084849
Abstract: BACKGROUND Three metastatic human melanoma cell lines generated from patient removed lymph nodes and spleen metastasis were established in our laboratory. OBJECTIVE To investigate the mechanisms enhancing the cytotoxic effects of Bleomycin (BLM), herpes simplex… read more here.
Keywords: lipofection; cell lines; gene; metastatic human ... See more keywords
Sulforaphane has an additive anticancer effect to FOLFOX in highly metastatic human colon carcinoma cells.
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DOI: 10.3892/or.2022.8420
Abstract: Colorectal cancer (CRC) is one of the most common malignancies worldwide. Patients with CRC may need chemotherapy (CTx) in a neoadjuvant, adjuvant or palliative setting through the course of the disease. Unfortunately, its effect is… read more here.
Keywords: metastatic human; effect; human colon; crc ... See more keywords