Lung‐Targeted Rnai Therapeutics: Lung‐Endothelium‐Targeted Nanoparticles Based on a pH‐Sensitive Lipid and the GALA Peptide Enable Robust Gene Silencing and the Regression of Metastatic Lung Cancer (Adv. Funct. Mater. 18/2019)
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DOI: 10.1002/adfm.201970121
Abstract: advanced materials that can achieve specific cellular targeting together with efficient intracellular trafficking for reaching target sites in the cytosol. In article number 1807677, Ikramy A. Khalil, Hideyoshi Harashima, and co-workers use nanoparticles modified with… read more here.
Keywords: lung; metastatic lung; lung endothelium; robust gene ... See more keywords
Timing of palliative care needs reporting and aggressiveness of care near the end of life in metastatic lung cancer: A national registry‐based study
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DOI: 10.1002/cncr.31536
Abstract: Early integration of palliative care for patients with metastatic lung cancer improves their quality of life and survival and reduces the aggressiveness of care near the end of life. This study examined the association between… read more here.
Keywords: end life; metastatic lung; palliative care; cancer ... See more keywords
C‐reactive protein and its association with depression in patients receiving treatment for metastatic lung cancer
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DOI: 10.1002/cncr.31859
Abstract: Depression is highly prevalent in lung cancer. Although there is a known association between inflammation and depression, this relationship has not been examined in patients with lung cancer who undergo treatment with immune and other… read more here.
Keywords: depression; reactive protein; metastatic lung; lung cancer ... See more keywords
Geographic variation in palliative care delivery among patients diagnosed with metastatic lung cancer in the USA: Medicare population-based study
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DOI: 10.1007/s00520-020-05549-z
Abstract: Purpose The USA has observed a significant increase in the use of palliative care for patients diagnosed with advanced cancer. However, it is unknown how geographic variation affects patients’ use of palliative care services. We… read more here.
Keywords: metastatic lung; geographic variation; palliative care; cancer ... See more keywords
Engineering Transferrin-Decorated Pullulan-Based Prodrug Nanoparticles for Redox Responsive Paclitaxel Delivery to Metastatic Lung Cancer Cells.
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DOI: 10.1021/acsami.2c18422
Abstract: Paclitaxel (PTX) remains a cornerstone in the treatment of locally advanced and metastatic lung cancer. To improve its therapeutic indices against lung cancer, novel redox-sensitive pullulan/PTX-based prodrug NPs (PULL-SS-PTX NPs) were accomplished, which were further… read more here.
Keywords: lung cancer; lung; pull ptx; metastatic lung ... See more keywords
Disparity in checkpoint inhibitor utilization among commercially insured adult patients with metastatic lung cancer.
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DOI: 10.1093/jnci/djac203
Abstract: BACKGROUND There is a lack of evidence from nationwide sample on the disparity of initiating immune checkpoint inhibitors (ICIs) after metastatic lung cancer diagnosis. METHODS We identified metastatic lung cancer patients diagnosed between 2015 and… read more here.
Keywords: lung cancer; cancer; metastatic lung; population ... See more keywords
Perforation of small intestine secondary to metastatic lung adenocarcinoma
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DOI: 10.1097/md.0000000000013469
Abstract: Rationale: About 50% of patients with a diagnosis of nonsmall cell lung carcinoma exhibit metastatic disease at the time of diagnosis. The preferential sites of extrapulmonary spread are the lymph nodes, liver, brain, adrenal glands,… read more here.
Keywords: lung adenocarcinoma; perforation; metastatic lung; secondary metastatic ... See more keywords
A nomogram model of postoperative prognosis for metastatic lung adenocarcinoma: A study based on the SEER database
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DOI: 10.1097/md.0000000000031083
Abstract: We have observed that patients with metastatic lung adenocarcinoma can obtain survival benefits from surgical resection of the primary tumor. A model was developed to evaluate the prognosis of patients. The patients with metastatic lung… read more here.
Keywords: group; metastatic lung; patients metastatic; lung adenocarcinoma ... See more keywords
The prognostic effect of metastasis patterns on overall survival in organ metastatic lung adenocarcinoma
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DOI: 10.1097/md.0000000000033297
Abstract: The effect of various metastases patterns on the prognosis of lung adenocarcinoma (AD) remains unknown. The purpose of our retrospective study is to determine whether various metastases patterns have a prognostic impact on patients with… read more here.
Keywords: metastasis; lung adenocarcinoma; effect; lung ... See more keywords
Choroidal metastasis as the presenting feature of metastatic lung carcinoma
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DOI: 10.1111/cxo.12950
Abstract: This is a case report of choroidal metastasis as the presenting feature of metastatic lung carcinoma in a young patient.A 32‐year‐old male presented with gradual‐onset painless progressive diminuti... read more here.
Keywords: metastasis presenting; feature metastatic; presenting feature; lung carcinoma ... See more keywords
Perforation of small intestine due to metastatic lung carcinoma
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DOI: 10.1136/bcr-2018-225708
Abstract: A 66-year-old woman with a history of 40 pack-year cigarette smoking and type II diabetes mellitus presented to the emergency department with unexplained weight loss and cough for a few weeks. These complaints constituted her first clinical… read more here.
Keywords: due metastatic; perforation small; metastatic lung; small intestine ... See more keywords