Clinical Outcomes of Metastatic Melanoma Treated With Checkpoint Inhibitors and Multisite Radiotherapy
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2017.2222
Abstract: Discussion | Although narrow-band UV-B phototherapy is the most widely used treatment modality for patients with vitiligo, it is associated with unnecessary UV exposure to normal skin.3 Because a majority of patients have limited involvement… read more here.
Keywords: tsl; clinical outcomes; 311 tsl; treatment ... See more keywords
Association of Anti-Programmed Cell Death 1 Antibody Treatment With Risk of Recurrence of Toxic Effects After Immune-Related Adverse Events of Ipilimumab in Patients With Metastatic Melanoma.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2020.2149
Abstract: Importance Since 2011, many patients with metastatic melanoma have been treated with ipilimumab therapy and have developed severe immune-related adverse events (AEs). Because several immune therapies are now available to treat metastatic melanoma, a better… read more here.
Keywords: therapy; related aes; immune related; metastatic melanoma ... See more keywords
Assessment of Trends in Second Primary Cancers in Patients With Metastatic Melanoma From 2005 to 2016
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.28627
Abstract: Key Points Question When compared with prior therapies, are immune checkpoint inhibitors for metastatic melanoma associated with development of second primary cancers? Findings In this cohort study of 5016 patients with metastatic melanoma between 2005… read more here.
Keywords: immune checkpoint; second primary; primary cancers; checkpoint inhibitors ... See more keywords
Use of First-Line Immune Checkpoint Inhibitors and Association With Overall Survival Among Patients With Metastatic Melanoma in the Anti–PD-1 Era
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.25459
Abstract: Key Points Question Following the US Food and Drug Administration’s approval of PD-1 immune checkpoint inhibitors (ICI) for metastatic melanoma, what were the utilization and overall survival associated with ICI in the first-line setting after… read more here.
Keywords: first line; overall survival; line; metastatic melanoma ... See more keywords
Joint action of miR‐126 and MAPK/PI3K inhibitors against metastatic melanoma
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12506
Abstract: Emerging data support the rationale of combined therapies in advanced melanoma. Specifically, the combined use of drugs with different mechanisms of action can reduce the probability of selecting resistant clones. To identify agents active against… read more here.
Keywords: combination; mir 126; pik; metastatic melanoma ... See more keywords
Metastatic melanoma of the heart: Retrospective cohort study and systematic review of prevalence, clinical characteristics, and outcomes
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5058
Abstract: Cardiac metastasis of melanoma is rare and typically diagnosed post‐mortem. Here we perform a retrospective cohort study and systematic review of patients with metastatic melanoma to characterize prevalence, clinical characteristics, and outcomes of cardiac metastasis. read more here.
Keywords: study systematic; systematic review; retrospective cohort; prevalence clinical ... See more keywords
Incidence, patterns of progression, and outcomes of preexisting and newly discovered brain metastases during treatment with anti–PD‐1 in patients with metastatic melanoma
Sign Up to like & getrecommendations! Published in 2019 at "Cancer"
DOI: 10.1002/cncr.32454
Abstract: Melanoma brain metastases (MBM) occur in up to 50% of patients with metastatic melanoma (MM) and represent a frequent site of systemic treatment failure for targeted therapies. However, to the authors' knowledge, little is known… read more here.
Keywords: brain metastases; progression outcomes; incidence patterns; patients metastatic ... See more keywords
Fine‐needle aspiration of metastatic melanoma presenting as bilateral breast cysts
Sign Up to like & getrecommendations! Published in 2017 at "Diagnostic Cytopathology"
DOI: 10.1002/dc.23666
Abstract: Melanoma is the second most common non‐hematopoietic malignancy after carcinomas to metastasize to the breast and often appears as a well‐circumscribed, dense nodule on imaging. Although metastatic lesions presenting as bilateral cysts have been reported,… read more here.
Keywords: breast; melanoma presenting; breast cysts; metastatic melanoma ... See more keywords
Surgical management of the neck in patients with metastatic melanoma in parotid lymph nodes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.25732
Abstract: The role and extent of neck dissection in patients with parotid metastatic cutaneous head and neck melanoma remain unclear. The aims of this study were to determine the incidence and patterns of cervical node involvement… read more here.
Keywords: neck; management neck; neck patients; patients metastatic ... See more keywords
Systematic evaluation of the predictive gene expression signatures of immune checkpoint inhibitors in metastatic melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23442
Abstract: Advances in immunotherapy, including immune checkpoint inhibitors (ICIs), have transformed the standard of care for many types of cancer including melanoma. ICIs have improved the overall outcome of melanoma patients; however, a significant proportion of… read more here.
Keywords: predictive biomarkers; checkpoint inhibitors; immune checkpoint; melanoma ... See more keywords
A Theranostic Cellulose Nanocrystal-Based Drug Delivery System with Enhanced Retention in Pulmonary Metastasis of Melanoma.
Sign Up to like & getrecommendations! Published in 2021 at "Small"
DOI: 10.1002/smll.202007705
Abstract: Metastatic melanoma can be difficult to detect until at the advanced state that decreases the survival rate of patients. Several FDA-approved BRAF inhibitors have been used for treatment of metastatic melanoma, but overall therapeutic efficacy… read more here.
Keywords: melanoma; cnc nps; 177 cnc; drug ... See more keywords