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Published in 2025 at "International journal of surgery"
DOI: 10.1097/js9.0000000000003852
Abstract: Extrahepatic cholangiocarcinoma (eCCA) is a highly malignant tumor with a propensity for metastasis, reflected in its estimated 5-year survival rate of 11%. Metastasis greatly impairs the effectiveness of cancer therapies and increases cancer-related deaths. Therefore,…
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Keywords:
metastasis;
tumor;
metastatic microenvironment;
extrahepatic cholangiocarcinoma ... See more keywords
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Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-5076
Abstract: Introduction: Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease associated with a 5-year survival rate of ~9%. The most notable clinical features of PDAC are its propensity for aggressive invasion, metastasis (mainly to the liver)…
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Keywords:
metastatic microenvironment;
apsc derived;
liver;
pro metastatic ... See more keywords
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Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.tumbody-ia013
Abstract: Mortality from cancer is almost exclusively due to metastasis to distant organs. Therefore, understanding the biology of tumor metastasis is the most significant challenge in cancer research today. The tumor microenvironment is central in supporting…
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Keywords:
metastatic microenvironment;
cancer;
microenvironment;
tumor ... See more keywords