Endostar Combined with Gemcitabine and Cisplatin Chemotherapy for Patients with Metastatic Nasopharyngeal Carcinoma: an Update
Sign Up to like & getrecommendations! Published in 2018 at "Translational Oncology"
DOI: 10.1016/j.tranon.2018.01.002
Abstract: OBJECTIVE: A previous phase-2 trial to assess the addition of Endostar to gemcitabine and cisplatin (GC) chemotherapy showed that it improves prognosis in metastatic nasopharyngeal carcinoma (M-NPC) but the study cohort was small. We wished… read more here.
Keywords: chemotherapy; cisplatin chemotherapy; gemcitabine cisplatin; day ... See more keywords
Effects of locoregional radiotherapy in de novo metastatic nasopharyngeal carcinoma: A real-world study
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DOI: 10.1016/j.tranon.2021.101187
Abstract: Highlights • Locoregional radiotherapy can prolong OS for patients with de novo metastatic nasopharyngeal carcinoma.• Nasopharyngeal carcinoma patients with oligometastic disease can benefit from locoregional radiotherapy rather than polymetastatic disease. read more here.
Keywords: metastatic nasopharyngeal; nasopharyngeal carcinoma; locoregional radiotherapy; novo metastatic ... See more keywords
Systemic therapies for recurrent or metastatic nasopharyngeal carcinoma: a systematic review
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DOI: 10.1038/bjc.2017.357
Abstract: Background:The majority of published studies in recurrent or metastatic nasopharyngeal carcinoma (RM-NPC) are single-arm trials. Reliable modelling of progression-free survival (PFS) and overall survival (OS) outcomes, therefore, is difficult. This study aim to analyse existent… read more here.
Keywords: recurrent metastatic; months model; metastatic nasopharyngeal; nasopharyngeal carcinoma ... See more keywords
Combination strategy exploration for prior treated recurrent or metastatic nasopharyngeal carcinoma in the era of immunotherapy
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DOI: 10.1038/s41598-024-52326-7
Abstract: To assess the efficacy and safety of the combination of immune checkpoint inhibitors (ICIs) and target therapy (anti-angiogenesis or EGFR inhibitors) as a second-line or subsequent treatment for recurrent or metastatic nasopharyngeal carcinoma (R/M NPC),… read more here.
Keywords: combination; recurrent metastatic; metastatic nasopharyngeal; target ... See more keywords
Risk-adapted locoregional radiotherapy strategies based on a prognostic nomogram for de novo metastatic nasopharyngeal carcinoma patients treated with chemoimmunotherapy
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DOI: 10.1038/s41598-024-54230-6
Abstract: To develop a prognostic nomogram for individualized strategies on locoregional radiation therapy (LRRT) in patients with de novo metastatic nasopharyngeal carcinoma (dmNPC) treated with chemoimmunotherapy. Ninety patients with dmNPC treated with chemoimmunotherapy and diagnosed between… read more here.
Keywords: novo metastatic; prognostic nomogram; risk; metastatic nasopharyngeal ... See more keywords
Capecitabine Monotherapy as Palliative Treatment for Patients with Recurrent/Metastatic Nasopharyngeal Cancer
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DOI: 10.1155/2022/6860413
Abstract: Background Numerous chemotherapeutic agents have antitumor activity in recurrent/metastatic (R/M) nasopharyngeal cancer (NPC). Evidence of capecitabine's effectiveness as monotherapy is limited. Capecitabine tolerability in solid malignancies has ethnic and geographical variability. We investigated capecitabine's tolerability… read more here.
Keywords: metastatic nasopharyngeal; capecitabine; capecitabine monotherapy; treatment ... See more keywords
Comparison Efficacy and Safety of Gemcitabine plus Cisplatin and 5-Fluorouracil plus Cisplatin for Metastatic Nasopharyngeal Carcinoma: A Meta-Analysis and Systematic Review
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/7233559
Abstract: Objective To compare the efficacy and safety of gemcitabine plus cisplatin (GP) and 5-fluorouracil plus cisplatin (PF) for metastatic nasopharyngeal carcinoma. Methods The clinical trials of GP and PF in the treatment of metastatic nasopharyngeal… read more here.
Keywords: nasopharyngeal carcinoma; plus cisplatin; metastatic nasopharyngeal; analysis ... See more keywords
Effect and safety of immunotherapy among elder patients (age ≥ 65) with recurrent or metastatic nasopharyngeal carcinoma
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DOI: 10.1186/s12885-025-14108-w
Abstract: The use of immune checkpoint inhibitors (ICIs) combined with chemotherapy constitutes the first-line treatment for recurrent or metastatic nasopharyngeal carcinoma (RM-NPC). However, elderly patients are underrepresented in the majority of related clinical trials. This retrospective… read more here.
Keywords: metastatic nasopharyngeal; recurrent metastatic; immunotherapy; nasopharyngeal carcinoma ... See more keywords
Stereotactic body radiotherapy to extend the clinical benefit of PD-1 inhibitors in recurrent/metastatic nasopharyngeal carcinoma.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e18013
Abstract: e18013Background: Emerging evidences have showed that immune checkpoint inhibitors lead to durable responses in a variety of advanced cancers, including recurrent/metastatic nasopharyngeal carcinom... read more here.
Keywords: recurrent metastatic; body radiotherapy; stereotactic body; radiotherapy extend ... See more keywords
GEM20110714: Final overall survival results of the phase III study of first-line gemcitabine plus cisplatin versus fluorouracil plus cisplatin in recurrent or metastatic nasopharyngeal carcinoma.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.6521
Abstract: 6521Background: GEM20110714, the first randomized, phase III study (NCT01528618) of systemic chemotherapy in recurrent or metastatic (R/M) nasopharyngeal carcinoma (NPC), reported significant reduc... read more here.
Keywords: recurrent metastatic; phase iii; plus cisplatin; iii study ... See more keywords
Camrelizumab Plus Apatinib in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma: An Open-Label, Single-Arm, Phase II Study
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DOI: 10.1200/jco.22.01450
Abstract: PURPOSE Immune checkpoint inhibitors combined with antiangiogenic therapy reportedly have potential synergistic antitumor activity. We investigated the activity and safety of this regimen for recurrent/metastatic nasopharyngeal carcinoma (NPC). METHODS This single-arm, Simon two-stage study enrolled… read more here.
Keywords: nasopharyngeal carcinoma; metastatic nasopharyngeal; single arm; patients recurrent ... See more keywords