Changing costs of metastatic non small cell lung cancer in the Netherlands.
Sign Up to like & getrecommendations! Published in 2017 at "Lung cancer"
DOI: 10.1016/j.lungcan.2017.10.005
Abstract: OBJECTIVES The primary objective of this study was to identify the total intramural cost of illness of metastatic non-small cell lung cancer (NSCLC) in the Netherlands between 2006-2012. Secondary objective was to identify whether changes… read more here.
Keywords: non small; metastatic non; metastatic nsclc; lung cancer ... See more keywords
Impact of radiotherapy on efficacy of anti-programmed death 1 (PD-1) antibodies in metastatic NSCLC
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz260.039
Abstract: Abstract Background The impact of radiotherapy (RT) on the efficacy and toxicity of immune checkpoint inhibitors in patients (pts) with metastatic non-small cell-lung cancer (NSCLC) is unclear. Methods We retrospectively identified pts with metastatic NSCLC… read more here.
Keywords: radiotherapy efficacy; treatment; radiotherapy; metastatic nsclc ... See more keywords
Treatment strategies based on different oligoprogressive patterns after immunotherapy failure in metastatic NSCLC
Sign Up to like & getrecommendations! Published in 2023 at "Therapeutic Advances in Medical Oncology"
DOI: 10.1177/17588359231156387
Abstract: Background: Oligoprogressive disease is recognized as the overall umbrella term; however, a small number of progressions on imaging can represent different clinical scenarios. This study aims to explore the optimal treatment strategy after immunotherapy (IO)… read more here.
Keywords: disease; metastatic nsclc; versus months; treatment ... See more keywords
Association between improvements in survival of metastatic NSCLC patients and targeted- and immuno-therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.15_suppl.9090
Abstract: 9090 Background: Significant improvements in mortality among NSCLC cancer patients in the US over the past two decades have recently been reported based on SEER data. The timing of these improvements led to suggestions that… read more here.
Keywords: alk; nsclc patients; improvements survival; metastatic nsclc ... See more keywords
STK11 (LKB1) mutations in metastatic NSCLC: Prognostic value in the real world
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DOI: 10.1371/journal.pone.0238358
Abstract: Background Mutations in STK11 (STK11m) and frequently co-occurring KRAS mutations (KRASm/STK11m) are associated with poor survival in metastatic NSCLC (mNSCLC) immuno-oncology trials. There are limited data regarding the prognostic significance of these mutations in a… read more here.
Keywords: real world; first line; krasm stk11m; metastatic nsclc ... See more keywords
Metronomic Oral Vinorelbine: An Alternative Schedule in Elderly and Patients PS2 With Local/Advanced and Metastatic NSCLC Not Oncogene-addicted
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DOI: 10.21873/invivo.12088
Abstract: Background: The MILES and ELVIS studies showed that vinorelbine is one of the best options for elderly patients with advanced non-small-cell-lung cancer (NSCLC). Oral vinorelbine at standard schedule (60-80 mg/m2/weekly) has good activity in terms… read more here.
Keywords: advanced metastatic; oral vinorelbine; vinorelbine; metronomic oral ... See more keywords
PLK1-mediated phosphorylation of β-catenin enhances its stability and transcriptional activity for extracellular matrix remodeling in metastatic NSCLC
Sign Up to like & getrecommendations! Published in 2023 at "Theranostics"
DOI: 10.7150/thno.79318
Abstract: Rationale: β-catenin is a component for cell adhesion and a transcriptional coactivator in epithelial-mesenchymal transition (EMT). Previously we found that catalytically active PLK1 drives EMT in non-small cell lung cancer (NSCLC), upregulating extracellular matrix factors… read more here.
Keywords: plk1; extracellular matrix; metastatic nsclc; phosphorylation ... See more keywords